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Nitric oxide synthases (NOSs), which catalyze the formation of the ubiquitous biological messenger molecule nitric oxide, represent unique cytochrome P-450s, containing reductase and mono-oxygenase domains within one polypeptide and requiring tetrahydrobiopterin as cofactor. To investigate whether tetrahydrobiopterin functions as an allosteric effector of… (More)

- A. Ballestrero, F. A. Berends, +27 authors R. Pittau
- 1996

Working group: E. Accomando, H. Anlauf, A. Ballestrero, F.A. Berends, E. Boos, F. Caravaglios, D. van Dierendonck, M. Dubinin, V. Edneral, F.C. Erné, J. Fujimoto, V. Ilyin, T. Ishikawa, S. Jadach, T. Kaneko, K. Kato, S. Kawabata, Y. Kurihara, D. Lehner, A. Leike, R. Miquel, G. Montagna, M. Moretti, T. Munehisa, O. Nicrosini, T. Ohl, A. Olchevski, G.J. van… (More)

- W Beenakker, F A Berends, +20 authors M Skrzypek
- 1996

2 On-Shell W-Pair Production and W Decay 6 2.1 Notation and conventions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2.2 Lowest order . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 2.3 Radiative corrections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2.3.1 Radiative electroweak O(α)… (More)

- P Klatt, S Pfeiffer, +6 authors B Mayer
- The Journal of biological chemistry
- 1996

Neuronal nitric-oxide (NO) synthase contains FAD, FMN, heme, and tetrahydrobiopterin as prosthetic groups and represents a multifunctional oxidoreductase catalyzing oxidation of L-arginine to L-citrulline and NO, reduction of molecular oxygen to superoxide, and electron transfer to cytochromes. To investigate how binding of the prosthetic heme moiety is… (More)

- Sven Grolik, Dirk Kalmring, Dietrich Lehner, Chiara Frigerio
- ECIS
- 2003

Knowledge is an important matter for consulting firms − as a resource, as a product or service, and as a trigger for internal value creation processes. Therefore, a strategy for management and utilisation of knowledge in its different state is needed. It is sensible to assume, that this strategy is strongly influenced by a respective consulting firm’s… (More)

- G E MOORE, D F LEHNER, Y KIKUCHI, L A LESS
- Science
- 1962

A melanotic cell line derived from a malignant melanoma of the golden hamster has retained its ability to produce melanin in vitro. This cell line provides an opportunity for studying the synthesis of melanin under various controlled conditions. The modal chromosome number in this cell line is 68.

- D Lehner, P Zipper, G Henriksson, G Pettersson
- Biochimica et biophysica acta
- 1996

Limited proteolysis of cellobiose dehydrogenase (CDH) from the white rot fungus Phanerochaete chrysosporium by papain cleaves the enzyme into two fragments containing flavin (FAD) and heme, respectively. Small-angle X-ray scattering (SAXS) was employed to investigate size and shape of intact CDH and of its fragments in solution. The largest dimension of CDH… (More)

A cross-section calculation for the Standard Model reaction ee → (ZZ) → f1f̄1f2f̄2 including the effects of the finite Z width and initial state radiative corrections is presented. The angular phase space integrations are performed analytically, leaving the invariant masses for numerical integration. Semi-analytical and numerical results in the energy range… (More)

We study Standard Model four-fermion production in e+e− annihilation at LEP2 energies and above using a semi-analytical approach. We derive the complete QED initial state corrections (ISR) to the reactions e+e− → (Z0Z0) → f1f̄1f2f̄2 and e+e− → (W+W−) → f̄u 1 fd 1 fu 2 f̄d 2 with f1 6= f2 and fi 6= e±, (−) νe . As compared to the well-known universal… (More)

- D. Bardin, J. Biebel, D. Lehner, A. Leike, A. Olchevski, T. Riemann
- 1996

We describe version 2.0 of the Fortran program GENTLE/4fan for the semi-analytic computation of cross-sections and distributions in four-fermion production in e+e− annihilation. GENTLE/4fan covers all charged current and neutral current fourfermion final states with no identical particles, no electrons, and no electron neutrinos in the final state. Initial… (More)