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It is well established that ErbB1 and ErbB2 can cooperate in mammary epithelial cell transformation. Therefore, to understand how ErbB1/ErbB2 signaling contributes to this process, we used the ErbB… Expand
We have used quinazoline inhibitors of the epidermal growth factor receptor (EGFR) tyrosine kinase to study the link between EGFR signaling and G1 to S traverse. Treatment of A431 and MDA-468 human… Expand
Nach zwanzig Jahren diskursanalytischer Forschung in Frankreich und mehr als funfzehn Jahre nach der Kenntnisnahme und Diskussion dieser Forschungsrichtung in Deutschland scheint die Diskursanalyse… Expand
Signaling by the HER-2 proto-oncogene product results in the activation of several biochemical pathways, which in turn modulate the expression and function of cell cycle regulators. These alterations… Expand
Frame semantics is an important recent development in linguistic theory that links linguistics, cognitive psychology, general cognitive science, and AI research. This handbook-style introductory… Expand
Tyrosine kinases play a role in normal cellular regulatory processes. However, aberrant tyrosine kinase activity can lead to cellular transformation and can be causally associated with tumor… Expand