Dietmar Neubacher

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BACKGROUND This study investigated the cardiovascular (CV) safety profile of the dipeptidyl peptidase (DPP)-4 inhibitor linagliptin versus comparator treatments. METHODS This was a pre-specified meta-analysis of CV events in linagliptin or comparator-treated patients with type 2 diabetes mellitus (T2DM) from eight Phase 3 studies. All suspected CV events(More)
BACKGROUND The cardiovascular (CV) safety of linagliptin was evaluated in subjects with type 2 diabetes (T2DM). METHODS Pre-specified patient-level pooled analysis of all available double-blind, randomized, controlled trials, ≥ 12 weeks' duration (19 trials, 9459 subjects) of linagliptin versus placebo/active treatment. Primary end point: composite of(More)
In the following a summary of the complete conceptual model for the port problem is given. The problem consists of two ports, one for tankers and one for container ships. In both ports tugboats operate to berth and de-berth ships. The main sequence of activities can be described as follows. Tankers and container ships arrive at a corresponding harbor site(More)
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