Dieter Meissner

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To investigate a possible influence of GB virus C (GBV-C) in immunocompromised patients, the prevalences of GBV-C RNA and anti-E2 antibody in 197 human immunodeficiency virus (HIV)-infected patients and in 120 control blood donors were studied. GBV-C RNA was detected in 33 of 197 HIV-infected patients (16.8%) compared with 1 in 120 blood donors (0.8%) (P <(More)
BACKGROUND Sodium selenite may play a role in reduction of enhanced oxygen free radicals in the early phase of experimental acute pancreatitis. The aim of the study was to determine whether ERCP induced pancreatitis can be used as a human model for early acute pancreatitis and if a prophylactic antioxidant therapy with sodium selenite or a prophylactic(More)
BACKGROUND Recent studies presented evidence that activation of oxygen derived free radicals occurs in patients with acute pancreatitis. The purpose of this study was to evaluate the effect of sodium selenite as a possible antioxidant therapy in acute pancreatitis. PATIENTS AND METHOD 16 patients with moderate form of acute pancreatitis received a high(More)
The late organ complications in diabetic patients are associated with enhanced oxidation of low-density lipoproteins (LDL). The role of vitamin and trace metal concentrations in this process is not clear. Therefore, we compared the oxidative susceptibility and alpha-tocopherol concentration of LDL with the levels of glycated hemoglobin (HbA1c), copper and(More)
GB virus C (GBV-C) is a newly discovered RNA virus related to the Flaviviridae family. Although GBV-C is not yet associated with any cause of liver disease, a humoral immune response against the GBV-C envelope 2 (E2) protein has been observed. Therefore, we studied the prevalence and clinical relevance of GBV-C RNA and anti-E2 antibodies in patients(More)
□Hintergrund: Im Frühstadium der experimentellen akuten Pankreatitis werden Sauerstoffradikale vermehrt freigesetzt. Radikalfangern wie dem Selen wird eine effiziente Verringerung dieser Radikale zugeschrieben. Ziel unserer Studie war es zu untersuchen, ob die ERCP-bedingte Pankreatitis als Modell für die frühe Phase der akuten klinischen Pankreatitis(More)
As a result of physical violence to exposed regions of skin (beating, grabbing) it was possible to effect a mutual transfer of epithelial cells between probands. The majority of these cells were corneocytes with a minimal incidence of nucleated stratum granulosum cells. Punching onto foil-covered sandbags resulted in a comparable transfer of cells. Punches(More)
Objective: Oxidation of low density lipoproteins (LDL) is thought to be an important step in the development of atherosclerosis. Trace metals are involved in oxidative processes. It was of interest to determine whether lipid-lowering therapy with fluvastatin, a potent HMGCoA reductase inhibitor, affected LDL oxidation and trace metal levels. Methods: Twenty(More)
BACKGROUND To ensure a correct interpretation of patient's data the regional differences in the supply with selenium have to be taken into consideration. PATIENTS AND RESULTS In 256 healthy women and men from the area of Dresden aged 20 to 62 years the selenium reference values were examined in blood serum by 1.09 +/- 0.17 (0.75 to 1.43) and in whole(More)
It was hypothesised that choice reaction-time (CRT) testing would cause salivary [K+]/[Na+] to increase. Relative contributions of [K+] and [Na+] to ratio changes were investigated in 23 hypertensives and ten hospital staff. Changes in post-rest and post-test ionic concentrations and [K+]/[Na+], replicated earlier studies. Phasic [K+]/[Na+] changes were(More)