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The optimal stimulation site in subthalamic deep brain stimulation (STN-DBS) was evaluated by correlation of the stereotactic position of the stimulation electrode with the electrophysiologically specified dorsal STN border. In a series of 25 electrodes, best clinical results with least energy consumption were found in contacts located in the dorsolateral(More)
Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an established therapy for Parkinson's disease (PD). A manic episode with psychotic symptoms induced by STN-DBS occurred in a previously psychiatrically healthy patient, focusing on the role of STN-DBS in influencing not only motor but also emotional behaviour.
Unlike the mechanisms involved in the death of neuronal cell bodies, those causing the elimination of processes are not well understood owing to the lack of suitable experimental systems. As the neurotrophin receptor p75(NTR) is known to restrict the growth of neuronal processes, we engineered mouse embryonic stem (ES) cells to express an Ngfr (p75(NTR))(More)
—Although the vast majority of research in human-computer interaction often involves only our senses of sight and hearing, with sporadic forays into touch, future laboratories used in engineering education will mostly benefit from developments beyond video and sound. Tangible and embedded interaction, augmented and mixed reality characterizes ultimate(More)
Extended and networked enterprises distribute the design of products, planning of the production process, and manufacturing regionally if not globally. The usual face-to-face work is going to be replaced, at least partly, if not totally, by computer mediated collaboration. Awaited are reduced problems of resolution cycle time, increasing productivity and(More)
The cells responsible for production of the male sex hormone testosterone, the Leydig cells of the testis, are post-mitotic cells with neuroendocrine characteristics. Their origin during ontogeny and regeneration processes is still a matter of debate. Here, we show that cells of testicular blood vessels, namely vascular smooth muscle cells and pericytes,(More)
SUMMARY Currently one of the most challenging aspects of human computer interaction design is the integration of physical and digital worlds in a single environment. This fusion involves the development of "Mixed Reality Systems " , including various technologies from the domains of augmented and virtual reality. In my talk I will present related concepts(More)
Research results of improving remote collaboration are presented. The results are based on a new concept of mixed reality. It is capable of to train collaborative work over remote sites. The collaborative environment makes use of the system named deriveSERVER, which has been developed by the Artec Research Center (University of Bremen). It is extended to(More)