Dieter Kübler

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Bone sialoprotein (BSP) and osteopontin (OPN) are important factors in the metastasis of breast cancer, which were examined as targets for antineoplastic therapy by siRNA. In addition, the effect of gene silencing on their transcription factor Runx2 and their interaction partners integrin β3 and matrix metalloproteinase 2 was studied. The effect of siRNAs(More)
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