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This is the first publication of the presence of Huntington's disease (HD) in Colombia. We studied four families comprising nine adult HD patients and 45 high risk adult offspring; all received complete physical, neurological and neuropsychological examinations. Among affected individuals, intensity of mental involvement varied in direct proportion with… (More)
INTRODUCTION Folstein's Mini Mental State Examination (MMSE) is widely used as screening test for cognitive impairment. OBJECTIVE To test a Spanish version of the MMSE in a population of high illiteracy rate. MATERIAL AND METHODS Population-based survey of a stratified random sample of urban and rural residents of five regions of Colombia, followed by… (More)
BACKGROUND Parkinson disease (PD) is a chronic multifaceted neurodegenerative disorder of adult onset that affects quality of life and places a burden on patients, caregivers, and society. In early disease, dopaminergic therapy improves motor symptoms, but as the disease progresses, symptoms tend to increase in frequency and severity, even with best medical… (More)
Mucopolysaccharidosis VI is an autosomal recessive lysosomal storage disorder associated with severe disability and premature death. The presence of a mucopolysaccharidosis-like disease in indigenous ethnic groups in Colombia can be inferred from archaeological findings. There are several indigenous patients with mucopolysaccharidosis VI currently receiving… (More)
BACKGROUND Pneumococcal conjugate vaccines (PCVs) are in the process of implementation in Latin America. Experience in developed countries has shown that they reduce the incidence of invasive and non-invasive disease. However, there is evidence that the introduction of PCVs in universal mass vaccination programs, combined with inappropriate and extensive… (More)
INTRODUCTION Our aim was to evaluate the impact of hyperproteic hypocaloric enteral feeding on clinical outcomes in critically ill patients, particularly on severity of organic failure measured with the Sequential Organ Failure Assessment (SOFA). MATERIALS AND METHODS In a double blind clinical trial, 80 critically ill adult patients were randomized to… (More)
Palabras clave: Recursos humanos, captura-recaptura, oferta de médicos especialistas, Colombia.