Diego Rosselli

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This is the first publication of the presence of Huntington's disease (HD) in Colombia. We studied four families comprising nine adult HD patients and 45 high risk adult offspring; all received complete physical, neurological and neuropsychological examinations. Among affected individuals, intensity of mental involvement varied in direct proportion with(More)
INTRODUCTION Folstein's Mini Mental State Examination (MMSE) is widely used as screening test for cognitive impairment. OBJECTIVE To test a Spanish version of the MMSE in a population of high illiteracy rate. MATERIAL AND METHODS Population-based survey of a stratified random sample of urban and rural residents of five regions of Colombia, followed by(More)
INTRODUCTION Our aim was to evaluate the impact of hyperproteic hypocaloric enteral feeding on clinical outcomes in critically ill patients, particularly on severity of organic failure measured with the Sequential Organ Failure Assessment (SOFA). MATERIALS AND METHODS In a double blind clinical trial, 80 critically ill adult patients were randomized to(More)
PURPOSE Appropriate caloric intake in critically ill patients receiving enteral nutrition is controversial. This study evaluates the impact of different caloric regimens on severity of organ failure measured with Sequential Organ Failure Assessment (SOFA). MATERIALS AND METHODS We conducted a randomized prospective controlled trial. Study population(More)
BACKGROUND Tobacco companies are focusing their interest in less developed countries. In the absence of governmental opposition, physicians are expected to lead tobacco control efforts. We studied Colombian medical students' smoking prevalence and tobacco attitudes. METHODS First- and fifth-year students from 11 medical schools in seven Colombian cities(More)
OBJECTIVE Antibodies against water channel protein aquaporin 4 (AQP4) in astrocytes play a role in the etiology and physiopathology of neuromyelitis optica (NMO); detection of this immunoglobulin in serum is highly suggestive of this diagnosis. There are several immunoassays to detect the antibody with different sensitivities and specificities. We conducted(More)
BACKGROUND Parkinson disease (PD) is a chronic multifaceted neurodegenerative disorder of adult onset that affects quality of life and places a burden on patients, caregivers, and society. In early disease, dopaminergic therapy improves motor symptoms, but as the disease progresses, symptoms tend to increase in frequency and severity, even with best medical(More)
INTRODUCTION The burden of Streptococcus pneumoniae infections is highest in children. Estimates in adult population are uncommon. We determined the burden of disease associated with pneumococcus in adults in Colombia in year 2008. METHODOLOGY Using different data sources (official mortality records, medical databases, published literature and local(More)
BACKGROUND Pneumococcal conjugate vaccines (PCVs) are in the process of implementation in Latin America. Experience in developed countries has shown that they reduce the incidence of invasive and non-invasive disease. However, there is evidence that the introduction of PCVs in universal mass vaccination programs, combined with inappropriate and extensive(More)