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Evidence of prehistoric dentistry has been limited to a few cases, the most ancient dating back to the Neolithic. Here we report a 6500-year-old human mandible from Slovenia whose left canine crown bears the traces of a filling with beeswax. The use of different analytical techniques, including synchrotron radiation computed micro-tomography (micro-CT),(More)
The description of a Neanderthal hyoid from Kebara Cave (Israel) in 1989 fuelled scientific debate on the evolution of speech and complex language. Gross anatomy of the Kebara 2 hyoid differs little from that of modern humans. However, whether Homo neanderthalensis could use speech or complex language remains controversial. Similarity in overall shape does(More)
The presence of ring artifacts in X-ray computed microtomography affects the qualitative and quantitative analyses of the reconstructed images. Although digital image processing approaches to ring artifacts removal via direct filtering of the reconstructed images exist, in synchrotron radiation microtomography this issue is usually faced during the actual(More)
Concentric rings are among the most recurrent artifacts in X-ray computed microtomography imaging. Their presence have a negative impact on the quantitative and qualitative analyses of the data. An interesting approach for ring artifacts removal is based on direct filtering of the reconstructed slices. Slice filtering does not require additional imaging(More)
Quantitative assessment of trabecular bone structure based on magnetic resonance microimages requires a segmentation step, which is difficult to perform because of low signal-to-noise ratio and spatial signal inhomogeneities in these images. In this paper, we present the design of voxel classifiers based on statistical mixture models and classifiers using(More)
When considering the acquisition of experimental synchrotron radiation (SR) X-ray CT data, the reconstruction workflow cannot be limited to the essential computational steps of flat fielding and filtered back projection (FBP). More refined image processing is often required, usually to compensate artifacts and enhance the quality of the reconstructed(More)
Acellular scaffolds obtained via decellularization are a key instrument in regenerative medicine both per se and to drive the development of future-generation synthetic scaffolds that could become available off-the-shelf. In this framework, imaging is key to the understanding of the scaffolds' internal structure as well as their interaction with cells and(More)
Microtomographic (μ-CT) experiments can be performed in the so-called Propagation Based Imaging (PBI) modality by using a sufficiently coherent X-ray beam, such as the one obtained at e.g. third generation synchrotron laboratories or at enhanced liquid-metal-jet-anode micro focus facilities. Then, a quantitative relationship exists between the phase(More)
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