Diego A. Hartasánchez

Learn More
In contrast to the classical view of development as a preprogrammed and deterministic process, recent studies have demonstrated that stochastic perturbations of highly non-linear systems may underlie the emergence and stability of biological patterns. Herein, we address the question of whether noise contributes to the generation of the stereotypical(More)
Interlocus gene conversion is a major evolutionary force that drives the concerted evolution of duplicated genomic regions. Theoretical models successfully have addressed the effects of interlocus gene conversion and the importance of crossover in the evolutionary fate of gene families and duplications but have not considered complex recombination(More)
SUMMARY SeDuS is the first flexible and user-friendly forward-in-time simulator of patterns of molecular evolution within segmental duplications undergoing interlocus gene conversion and crossover. SeDuS introduces known features of interlocus gene conversion such as biased directionality and dependence on local sequence identity. Additionally, it includes(More)
Crossover is the most complicated of the standard genetic operators as well as one of the main operators in genetic algorithms. The role of the crossover operator has not been satisfactorily explained. It has not been easy to show if it is essential for the construction and exploitation of building blocks during evolution. In this paper we introduce an(More)
  • 1