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  • Mark J. Millan, Anthony Gobert, +5 authors Didier Cussac
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental…
  • 2003 (First Publication: 1 September 2003)
  • Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. It also interacted with h5-HT2B receptorsExpand
  • Mark J. Millan, Lisa Maiofiss, Didier Cussac, Valérie Audinot, Jean-A Boutin, Adrian Newman-Tancredi
  • Medicine, Chemistry
  • Journal of Pharmacology and Experimental…
  • 2002 (First Publication: 1 November 2002)
  • Because little comparative information is available concerning receptor profiles of antiparkinson drugs, affinities of 14 agents were determined at diverse receptors implicated in the etiology and/orExpand
  • Mark J. Millan, Adrian Newman-Tancredi, +9 authors Alain P Gobert
  • Psychology, Medicine
  • Synapse
  • 2000 (First Publication: 1 February 2000)
  • Herein, we evaluate the interaction of the alpha(2)-AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic,Expand
  • Mark J. Millan, Anthony Gobert, +6 authors G Méndez Lavielle
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 2000 (First Publication: 1 June 2000)
  • The benzopyranopyrrole S33084 displayed pronounced affinity (pK(i) = 9.6) for cloned human hD(3)-receptors, and >100-fold lower affinity for hD(2) and all other receptors (>30) examined. S33084Expand
  • Stéphane Vispé, Luc DeVries, +10 authors Christian Bailly
  • Biology, Medicine
  • Molecular Cancer Therapeutics
  • 2009 (First Publication: 1 October 2009)
  • Triptolide, a natural product extracted from the Chinese plant Tripterygium wilfordii, possesses antitumor properties. Despite numerous reports showing the proapoptotic capacity and the inhibition ofExpand
  • Adrian Newman-Tancredi, Didier Cussac, +4 authors Mark J. Millan
  • Medicine, Chemistry
  • Journal of Pharmacology and Experimental…
  • 2002 (First Publication: 1 November 2002)
  • The accompanying multivariate analysis of the binding profiles of antiparkinson agents revealed contrasting patterns of affinities at diverse classes of monoaminergic receptor. Herein, weExpand
  • Mark J. Millan, Adrian Newman-Tancredi, Yann Quentric, Didier Cussac
  • Psychology, Medicine
  • Psychopharmacology
  • 2001 (First Publication: 1 June 2001)
  • Abstract. Rationale: The benzazepine and "selective" dopamine D1 receptor antagonist, SCH23390 [(R)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-benzazepine-7-ol], shows significant affinityExpand
  • Mark J. Millan, L Seguin, Alain P Gobert, Didier Cussac, Mauricette Brocco
  • Medicine, Psychology
  • Psychopharmacology
  • 2003 (First Publication: 1 July 2004)
  • BackgroundThe role of dopamine D3/D2 receptors in the control of locomotion is poorly understood.ObjectivesTo examine the influence of selective antagonists at D3 or D2 receptors on locomotion inExpand