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  • Karine Wiegler, Christophe Bonny, Didier Coquoz, Lorenz Hirt
  • Medicine
  • Cerebrovascular Diseases
  • 2008
  • Background: XG-102 (formerly D-JNKI1), a TAT-coupled dextrogyre peptide which selectively inhibits the c-Jun N-terminal kinase, is a powerful neuroprotectant in mouse models of middle cerebral arteryContinue Reading
  • Nicolas Poirier, Gilles Blancho, +14 authors Bernard Vanhove
  • Biology, Medicine
  • The Journal of Immunology
  • 2016 (First Publication: 15 December 2016)
  • FR104 is a monovalent pegylated Fab′ Ab, antagonist of CD28, under development for treatment of transplant rejection and autoimmune diseases. In contrast to CD80/86 antagonists (CTLA4-Ig), FR104Continue Reading