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Acute hepatic and renal toxicity of dichlorobenzene isomers in Fischer 344 rats.

• Monica A Valentovic, John G. Ball, Dianne K. Anestis, E. Madan
• Journal of applied toxicology : JAT
• 1993

Studies were conducted to examine acute hepatic and renal toxicity of dichlorobenzene (DCB) structural isomers. Male Fischer 344 (F344) rats were injected with 2, 3 or 4 mmol kg-1 of 1,2-DCB, 1,3-DCB… (More)

In vitro nephrotoxicity induced by propanil.

• Gary O. Rankin, Christopher R Racine, Adam P. Sweeney, Alyssa M Kraynie, Dianne K. Anestis, John B Barnett
• Environmental toxicology
• 2008

Propanil is a postemergence herbicide used primarily in rice and wheat production in the United States. The reported toxicities for propanil exposure include methemoglobinemia, immunotoxicity, and… (More)

Nephrotoxicity induced by the R- and S-enantiomers of N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS) and their sulfate conjugates in male Fischer 344 rats.

• Gary O. Rankin, Dianne K. Anestis, Monica A Valentovic, Hang Sun, William E. Triest
• Toxicology
• 2007

The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) induces nephrotoxicity characterized as polyuric renal failure and mediated via metabolites arising from oxidation of the… (More)

Gender differences in acute N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS) and N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity in Fischer 344 rats.

• Suk Ki Hong, Dianne K. Anestis, +4 authors Gary O. Rankin
• Journal of toxicology and environmental health…
• 1998

N-(3,5-Dichlorophenyl)succinimide (NDPS) is an agricultural fungicide that induces nephrotoxicity as its major toxicity. NDPS is also a more potent nephrotoxicant in female than in male rats. The… (More)

Effect of dimethyl sulfoxide on N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity.

• Gary O. Rankin, K. W. Beers, +4 authors Patrick I Brown
• Toxicology
• 1995

Dimethyl sulfoxide (DMSO) is frequently used as a solvent to assist in dissolving compounds which are not readily soluble in other injection vehicles. The purpose of this study was to determine the… (More)

Comparison of the in vitro toxicity of dichloroaniline structural isomers.

• Monica A Valentovic, John G. Ball, Dianne K. Anestis, Gary O. Rankin
• Toxicology in vitro : an international journal…
• 1995

Acute exposure to certain dichloroaniline (DCA) isomers results in renal and hepatic toxicity in vivo. In the present study we examined whether dichloroaniline structural isomers were cytotoxic to… (More)

Modification of P450 activity and its effect on 1,2-dichlorobenzene toxicity in Fischer 344 rats.

• Monica A Valentovic, John G. Ball, Dianne K. Anestis, E. Madan
• Toxicology
• 1993

This study examined the contribution of biotransformation by the mixed function oxidase system on hepatic and renal toxicity of 1,2-dichlorobenzene (1,2-DCB). Male Fischer 344 (F344) rats (190-250 g)… (More)

Potentiation of 5-hydroxytryptamine-induced contraction in rat aorta by chlorpheniramine, citalopram and fluoxetine.

• Carl A. Gruetter, Stefan Lemke, Dianne K. Anestis, John L Szarek, Monica A Valentovic
• European journal of pharmacology
• 1992

This study examined the effects of chlorpheniramine, citalopram and fluoxetine on 5-hydroxytryptamine (5-HT)-induced contraction and 5-HT uptake in rat thoracic aortic rings in vitro.… (More)

The role of glucuronidation in N-(3,5-dichlorophenyl)succinimide (NDPS) nephrotoxicity: nephrotoxic potential of NDPS and NDPS metabolites in Gunn, Wistar, and Fischer 344 rats.

• Suk Ki Hong, Dianne K. Anestis, Cody Skaggs, Patrick I Brown, Gary O. Rankin
• Toxicology and applied pharmacology
• 1999

The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) is an acute nephrotoxicant in rats. Although the mechanism of NDPS nephrotoxicity is not clear, our previous studies have strongly… (More)

Sodium sulfate potentiates N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS) and N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity in the Fischer 344 rat.

• Suk Ki Hong, Dianne K. Anestis, John G. Ball, Monica A Valentovic, Patrick I Brown, Gary O. Rankin
• Toxicology
• 1999

The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) induces nephrotoxicity as its major toxicity in rats. Previous studies have shown that NDPS induces nephrotoxicity following… (More)

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