Dianming Jiang

Learn More
This retrospective study included 35 patients who had a nano-hydroxyapatite/polyamide (n-HA/PA) composite strut implanted for cervical reconstruction and fusion after corpectomy from 2006 to 2008. The average follow-up period was 38.5 months (range: 24-48 months). The Japanese Orthopedic Association score and visual analog pain scale score were(More)
The aims of this study were to expose the function of calcitonin gene-related peptide (CGRP) in the proliferation and intracellular communication of mesenchymal stem cells (MSCs), to observe the change in IGF-1, BMP-2 and their receptor in the MSCs cell with exogenous CGRP, and to explore whether exogenous CGRP will induce MSCs to express the osteoinduced(More)
BACKGROUND The treatment of displaced femoral neck fracture includes internal fixation and arthroplasty. However, which is the best surgical treatment for the elderly patient with displaced femoral neck fractures has been controversial. Our objective was to compare the clinical effects of internal fixation with that of arthroplasty for displaced femoral(More)
OBJECTIVE To retrospectively compare the efficacy of the titanium mesh cage (TMC) and the nano-hydroxyapatite/polyamide66 cage (n-HA/PA66 cage) for 1- or 2-level anterior cervical corpectomy and fusion (ACCF) to treat multilevel cervical spondylotic myelopathy (MCSM). METHODS A total of 117 consecutive patients with MCSM who underwent 1- or 2-level ACCF(More)
Novel and better vertebral body replacement constructs are always desired by surgeons. Endplate geometry is crucial for the design of those implants, but current literature on that topic is very scarce. The authors present a morphometric study of thoracolumbar vertebral endplates, the goal of which was to analyze the geometry of endplates from T10 inferior(More)
Although classified as benign, giant cell tumors of the bone (GCTB) may be aggressive, recur and even metastasize to the lungs. In addition, the pathogenesis and histogenesis remain unclear; thus, the driving factors behind the strong tumor growth capacity of GCTB require investigation. In the present study, the expression levels of hypoxia‐inducible factor(More)
Mesenchymal stromal progenitor cells (MSCs) are multipotent progenitors that can be isolated from numerous tissues. MSCs can undergo osteogenic differentiation under proper stimuli. We have recently demonstrated that bone morphogenetic protein 9 (BMP9) is one of the most osteogenic BMPs. As one of the least studied BMPs, BMP9 has been shown to regulate(More)
The anterior cruciate ligament, posterior cruciate ligament, cartilage and meniscus in human knee joint have poor healing ability. Accumulation of MMPs in the joint fluids due to knee injury has been considered as the main reason. Our previous experiments showed that synovium may be the major regulator of MMPs in joint cavity after injury. In this paper, we(More)
OBJECTIVE To explore the effect of tripterygium glycoside (TG) on the skeletal muscle atrophy and apoptosis after nerve allograft. METHODS Twenty Wistar male rats were adopted as donors, weighing 200-250 g, and the sciatic nerves were harvested. Fifty SD male rats were adopted as recipients, weighing 200-250 g. Fifty SD rats were made the models of 10 mm(More)
Functional polymorphisms of the osteoprotegerin (OPG) gene are known to be involved in bone mineral density and the development of osteoporosis; however, some conflicting results have been reported. The aim of this meta-analysis is to provide a relatively comprehensive assessment of the relationship between seven common OPG genetic polymorphisms (T149C,(More)