Filter Results:
- Full text PDF available (16)
Publication Year
1987
2018
- This year (3)
- Last 5 years (26)
- Last 10 years (38)
Publication Type
Co-author
Journals and Conferences
Brain Region
Cell Type
Method
Organism
Learn More
- Zhi Yao Xie, Wendy O Adamowicz, +7 authors Frank S. Menniti
- Neuroscience
- 2006
PDE10A is a recently identified phosphodiesterase that is highly expressed by the GABAergic medium spiny projection neurons of the mammalian striatum. Inhibition of PDE10A results in striatal… (More)
- Diane Stephenson, Douglas A Schober, E. Barry Smalstig, R E Mincy, Donald R. Gehlert, James A. Clemens
- The Journal of neuroscience : the official…
- 1995
In mammalian brain the expression of peripheral benzodiazepine receptors (PBRs) can be markedly induced following different types of neuronal injury. PBRs are believed to be expressed on non-neuronal… (More)
- Timothy M Coskran, Daniel Morton, +6 authors Diane Stephenson
- The journal of histochemistry and cytochemistry…
- 2006
A monoclonal antibody directed against the amino terminal of rat phosphodiesterase 10A (PDE10A) was used to localize PDE10A in multiple central nervous system (CNS) and peripheral tissues from mouse,… (More)
- Diane Stephenson, Karen Rash, +7 authors James Clemens
- Glia
- 1999
Many recent studies have emphasized the deleterious role of inflammation in CNS injury. Increases in free fatty acids, eicosanoids, and products of lipid peroxidation are known to occur in various… (More)
- Binhui Ni, Xiaolin Wu, +4 authors Steven M Paul
- Journal of cerebral blood flow and metabolism…
- 1998
The authors recently cloned a cDNA for an ICE/CED3-related cysteine protease from rat brain, which is closely related to human CPP32 (now designated caspase-3). In situ hybridization histochemistry… (More)
- Diane Stephenson, Sharon M O'Neill, +9 authors Daniel Morton
- Molecular autism
- 2011
BACKGROUND
The inbred mouse strain BTBR T+ tf/J (BTBR) exhibits behavioral deficits that mimic the core deficits of autism. Neuroanatomically, the BTBR strain is also characterized by a complete… (More)
- Diane Stephenson, Cynthia A Lemere, Dennis J Selkoe, James A. Clemens
- Neurobiology of disease
- 1996
Phospholipase A2 (PLA2) is the key enzyme that initiates the arachidonic acid cascade, which leads to the generation of multiple eicosanoid products. Many of these products are believed to play an… (More)
- Dewen Yang, Zhiyong Xie, +7 authors Thomas Bocan
- NeuroImage
- 2011
The purpose of this study was to determine if in vivo high resolution 3D MRI and localized (1)H MR spectroscopy (MRS) can detect brain findings resembling Alzheimer's disease in a transgenic mouse… (More)
- Diane Stephenson, Karen Rash, James A. Clemens
- Brain research
- 1992
The distribution of beta-amyloid precursor protein (APP) was examined immunocytochemically in rats subjected to focal cerebral ischemia by permanent occlusion of the middle cerebral artery. At 4 and… (More)
BACKGROUND AND PURPOSE
After global ischemia, brain levels of hydrogen peroxide, oxygen radicals, and the cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) are… (More)