Diane Ruschel Marinho

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The detection of exudates is a prerequisite for detecting and grading severe retinal lesions, like the diabetic macular edema. In this work, we present a new method based on mathematical morphology for detecting exudates in color eye fundus images. A preliminary evaluation of the proposed method performance on a known public database, namely DIARETDB1,(More)
In this work, we present a new fovea center detection method for color eye fundus images. This method is based on known anatomical constraints on the relative locations of retina structures, and mathematical morphology. The detection of this anatomical feature is a prerequisite for the computer aided diagnosis of several retinal diseases, such as Diabetic(More)
The identification of some important retinal anatomical regions is a prerequisite for the computer aided diagnosis of several retinal diseases. In this paper, we propose a new adaptive method for the automatic segmentation of the optic disk in digital color fundus images, using mathematical morphology. The proposed method has been designed to be robust(More)
A new adaptive morphological method for the automatic detection of the optic disk in digital color eye fundus images is presented in this paper. This method has been designed to detect the optic disk center and the optic disk rim. In our experiments with the DRIVE and DIARETDB1 databases, the proposed method was able to detect the optic disk center with(More)
Mucopolysaccharidoses (MPS) are rare genetic diseases caused by the deficiency of one of the lysosomal enzymes involved in the glycosaminoglycan (GAG) breakdown pathway. This metabolic block leads to the accumulation of GAG in various organs and tissues of the affected patients, resulting in a multisystemic clinical picture, sometimes including cognitive(More)
PURPOSE To evaluate the visual system of patients suffering from type I or VI mucopolysaccharidosis (MPS) by recording the visual evoked cortical potential (VECP). METHODS Two patients with MPS VI and 2 patients with MPS I were tested before and after enzyme replacement therapy (ERT). A control group of 20 subjects was tested for statistical comparison.(More)
Importance. Autologous serum (AS) eye drops are recommended for severe dry eye in patients with ocular surface disease. No description of the antioxidant balance of AS eye drops has been reported in the literature. Objective. This study sought to evaluate the total reactive antioxidant potential (TRAP) and concentration of reactive oxygen species (ROS) in(More)
An efficient detection of exudate lesions in color eye fundus images is an essential stage for grading the Diabetic Macular Edema automatically. In this work, we present a new automatic method based on mathematical morphology to locate exudate lesions. The proposed method was evaluated using the publicly available DIARETDB1 database, and it obtains 72.21%(More)
This paper presents a novel method for the detection of the fovea center in color fundus images. The method was evaluated using a set of 89 images from the DIARETDB1 project, which contains images presenting normal and pathological situations. Using the Mean Absolute Distance (MAD) as a metric, we report 7.37+/-8.89 (mean +/- standard deviation) detection(More)
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