Diane M Welsh

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The objectives of this study were (1) to evaluate the indications, complications and outcomes of multiple red cell transfusions (MrcTs) in cats; of these cats (2) to describe those that received massive transfusion and (3) compare them with those who received MrcTs over a longer time course. Twenty-seven cats were identified which received a total of 110(More)
Excitatory synaptic field potentials, induced by stimulating optic nerve fibers, were recorded from in vitro preparations of the optic tectum of the frog. Bath-applied N-methyl-D-aspartate (NMDA), glutamate or quisqualate elicited transient enhancement in these field potentials, followed by a sustained depression reversible on washout. Responses to(More)
Although the use of heat in cancer therapy is not a new concept, recent advances in technology have allowed refinement and revival of this useful modality. This article reviews the biologic basis for heating, the rationale for combining hyperthermia with other brain tumor therapies, and various methods used to produce hyperthermia in brain tumor treatment.(More)
The aims of this study of 24 normotensive subjects were: to compare a free-operant with a discrete-trials training format; to determine the most effective training procedure by comparing instrumental conditioning with instructional set and a control; to see if both increases and decreases in blood pressure could be brought under discriminative control, and(More)
Interstitial hyperthermia therapy, the application of heat to control or destroy tumor tissue, is under investigation as an adjuvant treatment for recurrent intracranial malignancies. A brief review of the biologic effects and detailed information of one technique used to treat brain tumors are presented. Management of patients receiving hyperthermia is(More)
Malignant glioma is a devastating disease which presents a clinical challenge to physicians and neuroscience nurses. It carries a dismal prognosis, with a median survival of only nine months following application of conventional therapies of surgical resection, radiotherapy and chemotherapy. Hyperthermia is the application of sufficient heat to raise the(More)
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