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Sestrin2 Protein Positively Regulates AKT Enzyme Signaling and Survival in Human Squamous Cell Carcinoma and Melanoma Cells*
Background: The role of Sestrin2 (Sesn2) in skin squamous cell carcinoma (SCC) and melanoma is unknown. Results: Sesn2 increases AKT activation and resistance to UVB and chemotherapeutics and isExpand
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Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge.
BACKGROUND Skin barrier integrity requires a highly coordinated molecular system involving the structural protein filaggrin (FLG). Mutational loss of the skin barrier protein FLG predisposes subjectsExpand
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I-123 Whole Body Scanning: Case Report and Discussion
Purpose: In managing differentiated thyroid carcinoma, concern over the stunning that may occur with traditional whole body imaging using I-131 has fostered an interest in using I-123 for thisExpand
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An ovarian cancer companion [PERDU]