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The authors hypothesized that at-risk individuals identified on the basis of their Chapman scale scores would be diagnosed with schizophrenia-spectrum disorders at follow-up. In the present study, the authors interviewed 135 young adults approximately 5 years following their initial assessment. The at-risk groups included high scorers on the Perceptual(More)
The nature of the affective deficit that characterizes social anhedonia is not well understood. Emotionally evocative visual stimuli were presented to undergraduates identified as anhedonic or normal, based on their scores on the revised Social Anhedonia Scale. The affective stimuli were chosen to elicit positive and negative emotion; a subset of slides(More)
BACKGROUND Identifying endophenotypes of schizophrenia will assist in the identification of individuals who are at heightened risk for the disorder. Investigators have proposed antisaccade task deficits as an endophenotypic marker of schizophrenia. However, the diagnostic specificity and the temporal stability of the task deficit are unresolved issues. To(More)
This review focuses on saccade research with adult psychiatric patients. It begins with an introduction of the various types of saccades and the tasks used to evoke them. The functional significance of the different types of eye movements is briefly discussed. Research findings regarding the saccadic performance of different adult psychiatric patient(More)
The domain-specificity of working memory was examined in psychosis-prone individuals with elevated social anhedonia scores. A group of individuals with deviant scores on the revised Social Anhedonia Scale (n=43) were compared with a normal control group (n=39) on delayed match-to-sample tasks involving spatial, identity, and affective information. The(More)
Individuals who scored high on Perceptual Aberration-Magical Ideation Scales (Per-Mag; n = 90), the Social Anhedonia Scale (SocAnh; n = 39), and control participants (n = 89) were administered saccadic refixation (prosaccade) and saccadic suppression (antisaccade) tasks. Eye movements were scored in terms of error rates and latency. None of the groups(More)
The present study examined spatial working memory and Wisconsin Card Sorting Test (WCST) performance in psychosis-prone individuals, either those with extremely high scores on the Social Anhedonia Scale (SocAnh; n = 49) or deviant scores on the Perceptual Aberration-Magical Ideation Scales (Per-Mag; n = 66). Sixty-three individuals with normal scores on the(More)
Eye tracking dysfunction (ETD) is one of the most widely replicated behavioral deficits in schizophrenia and is over-represented in clinically unaffected first-degree relatives of schizophrenia patients. Here, we provide an overview of research relevant to the characterization and pathophysiology of this impairment. Deficits are most robust in the(More)
To date, the research literature has yielded conflicting reports regarding the specificity of antisaccade deficits to schizophrenia. We sought to examine antisaccade and working memory task performance in schizophrenia patients and bipolar patients, as well as to examine the relationship between the two tasks in both patient populations. Thirty-four(More)
BACKGROUND Although there have been several investigations of spatial working memory performance in schizophrenia patients, there have been considerably fewer studies of object working memory. The purpose of the present investigation was to evaluate the domain specificity of nonverbal working memory impairment in schizophrenia patients. METHODS Delayed(More)