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- Diane Bristol
- Journal of biopharmaceutical statistics
- 1991

The distance between two variances is usually measured using the ratio, and a confidence interval for this ratio can be used to measure its magnitude. For a two-by-two crossover study, specialâ€¦ (More)

- Diane Bristol
- Journal of biopharmaceutical statistics
- 1996

The problem of establishing the equivalence of an experimental treatment to a control with respect to a binary ("success" or "failure") response variable may be solved using an approximate (1-alpha)â€¦ (More)

- Diane Bristol
- Statistics in medicine
- 1989

Although estimation and confidence intervals have become popular alternatives to hypothesis testing and p-values, statisticians usually determine sample sizes for randomized clinical trials byâ€¦ (More)

- Diane Bristol
- Journal of biopharmaceutical statistics
- 1999

When the classical approach of testing the null hypothesis of equality is used and the results are not statistically significant, formal conclusions regarding the "closeness" of the treatments cannotâ€¦ (More)

- Diane Bristol
- Journal of biopharmaceutical statistics
- 1993

Rubinstein et al. presented a procedure for determining the required duration of accrual for a clinical trial comparing the survival distributions of two treatments using a classical hypothesisâ€¦ (More)

- P Y Chi, Diane Bristol, J V Castellana
- Statistics in medicine
- 1986

We consider a fixed-sample parallel-group clinical trial with an interim analysis that tests H0:mu x = mu y against H1:mu x less than mu y. If we do not reject at the interim analysis, then theâ€¦ (More)

- Diane Bristol, J V Castellana
- Statistics in medicine
- 1990

The variable 'walking time to moderate angina' on an exercise stress test is the primary means to judge the efficacy of new treatments for angina pectoris. Unfortunately, 'walking time to moderateâ€¦ (More)

- Diane Bristol
- Controlled clinical trials
- 1989

When a clinical trial is to be conducted to compare more than one experimental treatment to a control treatment, Dunnett's two-sided multiple comparison procedure may be proposed to perform theâ€¦ (More)

- Diane Bristol
- Controlled clinical trials
- 1988

Wieand and Therneau (Controlled Clin Trials 8:20-28, 1987) proposed a technique for conducting a clinical trial to test the equality of response rates for two treatments using a one-sided test withâ€¦ (More)

- Diane Bristol, Hima Patel
- Statistics in medicine
- 1990

For clinical trials that entail observations at successive visits for the occurrence of a side effect, this paper considers a likelihood-based method to compare side effect incidence rates. Theâ€¦ (More)