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BACKGROUND Therapies to improve outcomes following peripheral nerve injury are lacking. Prolonged denervation of muscle and Schwann cells contributes to poor outcomes. In this study, the authors assess the effects of growth hormone therapy on axonal regeneration, Schwann cell and muscle maintenance, and end-organ reinnervation in rats. METHODS Male(More)
A dvances in medicine are driven by propagation of research and dissemination of meaningful results from basic science, clinical, or translational studies. Although a randomized controlled trial has the highest power, this is not the most frequently conducted study method in surgery, as randomized trials are often not feasible due to disease infrequen-cy or(More)
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