Diana Nõmmemees

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INTRODUCTION Annexin A5 is an essential component of placental integrity that may potentially mediate susceptibility to phenotypes of compromised pregnancy. A promoter haplotype termed M2 of the coding gene ANXA5 has been implicated in various pregnancy complications such as preeclampsia and recurrent pregnancy loss (RPL), however with inconclusive results.(More)
We thank the Editors for the invitation to write an accompanying response to a Commentary by Markoff et al. (2016) on our recently published genetic association study with negative results (Nagirnaja et al., 2015). Our study aimed to assess the robustness of the association between the “haplotype M2” of the Annexin A5 (ANXA5) gene promoter and increased(More)
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