Diana Isabel Silva

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Serine protease inhibitors (SERPINs) are a superfamily of highly conserved proteins that play a key role in controlling the activity of proteases in diverse biological processes. The SERPIN cluster located at the 14q32.1 region includes the gene coding for SERPINA1, and a highly homologous sequence, SERPINA2, which was originally thought to be a pseudogene.(More)
Sir, Extended-spectrum b-lactamase (ESBL)-producing Enterobacte-riaceae have been recognized as significant nosocomial pathogens during recent decades. 1 The spread of these organisms is worrisome since they might also transfer antibiotic resistance genes among different hosts and environments. In this work, we describe the occurrence of ESBLs and integrons(More)
Y1 receptor (Y1R)-signalling pathway plays a pivotal role in the regulation of bone metabolism. The lack of Y1R-signalling stimulates bone mass accretion that has been mainly attributed to Y1R disruption from bone-forming cells. Still, the involvement of Y1R-signalling in the control of bone-resorbing cells remained to be explored. Therefore, in this study(More)
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