- Full text PDF available (2)
We performed a 1-year prospective study of 807 consecutive infants admitted to a regional neonatal intensive care unit to determine the frequency, natural history, mechanism(s), and cause of thrombocytopenia. Thrombocytopenia developed in 22% of the infants. The platelet count nadir usually occurred by day 4 and resolved by day 10. Possible mechanisms… (More)
In Colombia, diabetes mellitus is a public health program for those responsible for creating and implementing strategies for prevention, diagnosis, treatment, and follow-up that are applicable at all care levels, with the objective of establishing early and sustained control of diabetes. A clinical practice guide has been developed following the broad… (More)
The diabetogenic D variant of encephalomyocarditis virus (EMC-D) was previously shown to differ from the non-diabetogenic B variant (EMC-B) by 14 nucleotides out of 7829 bases. Similar approaches with a new nondiabetogenic variant, EMC-DV1, obtained by plaque purification of the EMC-D variant stock pool, enabled us to narrow down further the possible… (More)
This article summarizes the main features in the investigation of polymorphic behaviour of pharmaceuticals and emphasizes the role of combined thermoanalytical techniques for proper interpretation of complex problems. The examples illustrate the quality of information gained in relation to ther-modynamic and kinetic factors.
We describe the case of a boy who presented with clinical features of lymphadenitis accompanied by a lymphocytic leukemoid reaction of suppressor/cytotoxic T-cell phenotype. Progressive involvement of the bone marrow, liver, and spleen, and subsequently parotid and lacrimal glands, in the disease process, suggested the alternative diagnosis of malignant… (More)