Di Yu

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Sepia ink oligopeptide (SIO) is a tripeptide extracted from Sepia ink. To test the hypothesis that SIO inhibits prostate cancer by inducing apoptosis, the effects of SIO on the proliferation of three human prostate cancer cell lines were examined using a CCK-8 assay. SIO significantly inhibited the proliferation of DU-145, PC-3 and LNCaP cells in a time-(More)
OBJECTIVE To investigate the effect of age and gender on olfactory and gustatory function and to establish test methodology and normative values in Chinese subjects. STUDY DESIGN Cross-sectional study. SETTING The center laboratory and the Department of Otolaryngology-Head & Neck Surgery, Beijing Tongren Hospital. SUBJECTS AND METHODS The T&T(More)
In the present study, serum samples from 650 goats were collected from five counties between May and June 2012 and antibodies to Toxoplasma gondii were detected by indirect haemagglutination assay; 58 (9%) had antibodies to T. gondii with antibody titres of 1:64 to 1:1024. Seropositive samples were distributed in all five counties: seroprevalences in(More)
Vascular endothelial growth factor (VEGF) polymorphisms, specifically +405G/C (rs2010963), reportedly influence the risk for various digestive cancers. However, the consequences of these polymorphisms remain controversial and ambiguous. Therefore, we performed a meta-analysis of 11 studies with VEGF +405G/C genotyping on 2,862 patients and 3,028 controls(More)
BACKGROUND To examine changes of chemical sensory functions in patients with dysosmia. MATERIAL/METHODS The 272 study subjects included 98 healthy volunteers, 86 subjects with hyposmia and 88 subjects with functional anosmia. Their chemical sensory functions were examined using olfactory event-related potentials (oERPs), trigeminal event-related(More)
BACKGROUND We conducted this meta-analysis to address the open question of a possible association between maternal socioeconomic status and congenital heart defects (CHDs). METHODS We searched MEDLINE and EMBASE from their inception to January 1, 2014 for case-control and cohort studies that assessed the association between maternal socioeconomic status(More)
OBJECTIVES To establish the normal value of Sniffin' Sticks test in Chinese population and to explore it's clinical application in China. METHODS One hundred and five healthy volunteers were choosen from the department of physical examination of Beijing Tongren Hospital between 2007 and 2013. Another 165 patients complained of abnormal olfactory function(More)
OBJECTIVE Nicorandil exerts a protective effect on ischemia-reperfusion (I/R) injury in the brain and kidney through anti-apoptotic mechanisms. However, the mechanism by which nicorandil protects against I/R injury induced by deep hypothermic low flow (DHLF) remains unclear. METHODS We used a cerebral I/R model induced by DHLF to determine the(More)
Zika virus (ZIKV), a relatively elusive Aedes mosquito-transmitted flavivirus, had been brought into spotlight until recent widespread outbreaks accompanied by unexpectedly severe clinical neuropathies, including fetal microcephaly and Guillain–Barré syndrome (GBS) in the adult. In this review, we focus on the underlying cellular and molecular mechanisms by(More)