Di Pan

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BACKGROUND Parkinson's disease (PD) is the most prevalent movement disorder of the central nervous system, and affects more than 6.3 million people in the world. The characteristic motor features include tremor, bradykinesia, rigidity, and impaired postural stability. Current therapy based on augmentation or replacement of dopamine is designed to improve(More)
Although, the tremor of Parkinson's disease (PD) usually, but not always, differs from essential tremor (ET), there is no simple bedside test to distinguish PD from ET. We believe we have made such an observation. We studied 50 consecutive tremor-dominant PD patients (mean age: 63.4 years; mean disease duration: 4.9 years) and 35 consecutive ET patients(More)
According to the trolley side impact condition of UN R129 children restraint system, 2 kinds of simulation test methods were developed and the feasibility was verified. Based on the validated test method, the numerical simulation of side impact in 3 different restraint systems (5-point-car seat belt, 5-point-ISOFIX and shield-car seat belt) with Q3 child FE(More)
The Q1 dummy FE model was used to analyze different restraint paths of a G0+ group of CRS based on UN R129 rear facing sled test method. Four difference seatbelt restraint paths of the rear facing CRS were analyzed and the displacement of the CRS and physical injury parameters of Q1 dummy were compared. The results showed that the head maximum displacement(More)
As an advanced artificial intelligence technology, error back-propagation (BP) neural network algorithm has been widely applied to electronics, communications, automation and other fields. However, traditional BP neural network algorithm has the disadvantages, such as inclination to stick into local optima, and slow convergence, which exert a great impact(More)
Although gait and balance difficulties often occur together in Parkinson's disease (PD) patients, it is believed that they are actually two eparate symptoms. However, there are no simple tests to distinguish them. We have developed the self-administered Barrow Neurological Institute (BNI) question to distinguish between gait and balance issues in PD and it(More)