Dharmendra K. Mishra

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Morphea is a localized scleroderma variety which can be circumscribed or generalized and is characterized by sclerotic plaques developing on trunk and limbs. Surgery and radiation have been implicated as etiological factors for the development of morphea. Majority of the radiation-induced morphea cases have occurred in patients with breast cancer. The(More)
KRas is mutated in a significant number of human cancers and so there is an urgent therapeutic need to target KRas signalling. To target KRas in lung cancers we used a systems approach of integrating a genome-wide miRNA screen with patient-derived phospho-proteomic signatures of the KRas downstream pathway, and identified miR-193a-3p, which directly targets(More)
Eccrine syringofibroadenoma is a very rare benign tumour of acrosyringium of eccrine sweat duct. Based on the evidences of known etiological factors, two forms have been proposed; reactive and nonreactive. Reactive forms are rarer, and on even rarer occasions, trauma complicated by secondary nonspecific infections may lead to the development of reactive(More)
BACKGROUND Topical squaric acid dibutylester and diphenylcyclopropenone are still the most effective therapy for alopecia areata among widely available treatment options. Hence, it is important to know which one is more effective and safer between the two. AIMS The aim of this study was to compare topical squaric acid dibutylester and(More)
OBJECTIVES To detect cutaneous drug reactions through spontaneous reporting system in IGGMCand H, Nagpur and analyze them using standard assessment scales. MATERIALS AND METHODS An observational, prospective study was performed in patients attending dermatology OPD of IGGMC and H, Nagpur from 1(st) June 05 to 31(st) May 09. Patients were examined for(More)
— In power systems the next day's power generation must be scheduled every day, day ahead short-term load forecasting (STLF) is a necessary daily task for power dispatch. Its accuracy affects the economic operation and reliability of the system greatly. Under prediction of STLF leads to insufficient reserve capacity preparation and in turn, increases the(More)
Factor V Leiden mutation is the most common factor for venous thrombosis and it is associated with the increased risk of pregnancy loss. It's a single point mutation at nucleotide 1691 (GA) in exon 10 of Factor V gene, which produces an Arg 506 Gln substitution (R506Q). Although conventional sequencing is a widely used method to detect point mutation but(More)
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