Dharjath S Hameed

Learn More
[a] Ubiquitin (Ub) and ubiquitin-like proteins (Ubls) form a family of small and highly conserved post-translational modifiers that become linked to target proteins and thus modulate their function (such as degradation, trafficking and signalling). [1] The linkage between a Ub(l) and a target protein most frequently consists of an isopeptide bond between(More)
Post-translational modification of proteins with ubiquitin (Ub) and Ub chains controls protein breakdown by the proteasome, cellular localization of proteins, transcriptional activity, and DNA repair. [1] Ubiquitin is a highly conserved 76 amino acid protein that can be linked to target proteins through an isopeptide bond between the C-terminal carbox-ylate(More)
  • 1