Dharavath Ramesh

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The gamma-aminobutyric acid (GABA) receptor is an abundant neuronal receptor in the mammalian and invertebrate nervous systems and is associated with an inhibitory chloride ion channel. GABA is the endogenous neurotransmitter for the receptor and can trigger both fast activation and a reversible desensitization of the receptor. A series of photolabile(More)
Here we report the development and characterization of a new photolabile protecting group for the carboxyl group of neurotransmitters, 2-methoxy-5-nitrophenyl. The synthesis and characterization of a photolabile derivative of beta-alanine, caged beta-alanine, are described. beta-Alanine can activate the glycine receptor, a major inhibitory receptor in the(More)
Optimum utilization of the time after an accident which is golden hour serves as a measure of effectiveness of any emergency response service provider system. Recovery actions should be taken in time to reduce the loss of life and property. In spite of the reason that the service providers are well equipped, routing problems and traffic congestions breaks(More)
Fingerprint system is an important biometric technique for personal identification. The metric used for performance of identification techniques are directly scanned fingerprints or inked impression of fingerprints. The purpose is real-time, high confidence recognition of a person's identity by mathematical analysis of the random patterns that are visible(More)
The synthesis of a photosensitive blocking group for the carboxyl function of neurotransmitters, in this case glycine, is reported. The compound, 2-methoxy-5-nitrophenyl glycine ester (caged glycine), is photolyzed by a laser pulse at 308 or 337 nm within 3 microseconds and with a product quantum yield of 0.2. The compound is hydrolyzed in water with a time(More)
Blocking methodologies sometimes fail to stop malicious things. Attacks on data oriented applications are a serious threat as per the database management systems concern. The required objective of such environment is to find out the mean time attacks and patch up the failures within the stipulated time. This manuscript represents a failure (attacked)(More)