Dharam C. Jain

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Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these(More)
OBJECTIVE To investigate the medicative effects of medium-polar (benzene:acetone, 1:1, v/v) extract of leaves from Stevia rebaudiana (family Asteraceae) on alloxan-induced diabetic rats. MATERIALS AND METHODS Diabetes was induced in adult albino Wistar rats by intraperitoneal (i.p.) injection of alloxan (180 mg/kg). Medium-polar extract was administered(More)
Plumbago zeylanica Linn. (Plumbaginaceae) is used in the treatment of various inflammatory ailments in traditional medicines. In order to validate these ethnobotanical practices, the anti-inflammatory and antinociceptive activities of various leaf extracts (petroleum ether (60-80 degrees ), chloroform, acetone, ethanol, and aqueous) were studied using in(More)
A simple, precise and accurate high-performance thin-layer chromatographic method has been established for quantitative determination of quinine. Conditions were also optimized for best possible extraction of quinine via varying concentrations of diethyl amine in different solvents (n-hexane, chloroform, ethyl acetate and methanol) for maximum recovery of(More)
Petroleum ether (60 degrees-80 degrees C), chloroform, acetone, ethanol, aqueous and crude hot water extracts of the whole plant of C. dactylon and the two fractions of aqueous extract were tested for antihyperglycaemic activity in glucose overloaded hyperglycemic rats and in alloxan induced diabetic model at two-dose levels, 200 and 400 mg/kg (po)(More)
Various extracts including petroleum ether, chloroform, acetone, ethanol, aqueous and crude aqueous of barks of Acacia catechu (A. catechu) Willd (Leguminosae) and the two fractions of ethanolic extract were tested for antihyperglycaemic activity in glucose-loaded hyperglycaemic rats. The effective extract and fraction of A. catechu were subjected to(More)
OBJECTIVES To evaluate the antifertility properties of extracts of leaves of Plumbago zeylanica Linn. (Plumbaginaceae). METHODS The effects of petroleum ether, chloroform, acetone, ethanol and aqueous extracts of the leaves of P. zeylanica on the estrous cycle of rats were studied at two dose levels, namely, 200 and 400 mg/kg. The effective extracts were(More)
A simple, fast and precise quantitative high performance thin-layer chromatographic method has been developed for quantitative estimation of α-mangostin in fruit pericarp of Garcinia mangostana L. (Hypericaceae). Best solvent for extraction of α-mangostin optimized after screening with five solvents under same conditions using hot solid-liquid extraction(More)
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