Dhanusha Sabanathan

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PURPOSE Germ cell tumour (GCT) aetiology is uncertain and comprehensive epidemiological studies of GCT incidence are few. METHODS Nationwide data on all malignant GCTs notified to Australian population-based cancer registries during 1982-2011 were obtained. Age- and sex-specific, and World age-standardised incidence rates were calculated for paediatric(More)
ANZUP would like to thank Astellas for sponsoring the Best of the Best Awards. The awards are open to ANZUP members who have successfully submitted an abstract or concept and have been selected to present an oral or poster presentation at the Annual Scientific Meeting. Awards will be given based on the content, degree of innovation, significance, and(More)
Dose individualization of sunitinib has been proposed using therapeutic drug monitoring (TDM) or toxicity-adjusted dose (TAD). We prospectively studied aspects of TDM and TAD to inform future trials, namely (1) intrapatient variability (CV) of sunitinib and (2) feasibility of a TAD protocol. Sunitinib dose was adjusted to ensure grade 1 or 2 toxicity on(More)
AIM Sunitinib is a first-line treatment option for metastatic renal cell carcinoma (mRCC) funded by the Australian Pharmaceutical Benefits Scheme. Toxicities are common with the standard schedule leading to alternative dosing schedules to be suggested. We reviewed Australian treatment practices to evaluate the safety and outcomes of patients on a 2 weeks(More)
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