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Intranasal nerve growth factor enhances striatal neurogenesis in adult rats with focal cerebral ischemia
Investigation of the effect of intranasal NGF on striatal neurogenesis and functional recovery in adult rats with focal cerebral ischemia showed that treatment with IN NGF failed to increase cell proliferation but improved survival of newly generated cells in ipsilateral striatum and subventricular zones (SVZ). Expand
Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes to Ischemic Stroke Risk: A Meta-Analysis of 50 Case-Control Studies
A large meta-analysis of studies relating the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism to the risk of isChemic stroke indicates that the D allele of ACE I/D polymorphism is a low-penetrance susceptibility marker of ischemic stroke. Expand
Dietary fiber consumption and risk of stroke
It is indicated that dietary fiber consumption is inversely associated with stroke risk, and the effect is probably independent of conventional risk factors. Expand
Fluid-Attenuated Inversion Recovery Vascular Hyperintensity Topography, Novel Imaging Marker for Revascularization in Middle Cerebral Artery Occlusion
Higher FVH-ASPECTS measured outside the DWI lesion is associated with good clinical outcomes in patients undergoing endovascular treatment and can serve as an imaging selection marker for ET in acute middle cerebral artery occlusion. Expand
Montelukast Inhibits Matrix Metalloproteinases Expression in Atherosclerotic Rabbits
It was found that montelukast reduced neointimal formation, decreased macrophage accumulation, and increased smooth muscle cells, and attenuated the expression of M MP-2 and MMP-9 in atherosclerotic plaques, but it had no effect on plasma lipid levels. Expand
Severity assessment of intracranial large artery stenosis by pressure gradient measurements: A feasibility study
Fractional flow reserve (FFR)‐guided revascularization strategy is popular in coronary intervention. However, the feasibility of assessing stenotic severity in intracranial large arteries usingExpand
Atorvastatin Reduces Plaque Vulnerability in an Atherosclerotic Rabbit Model by Altering the 5-Lipoxygenase Pathway
Atorvastatin may stabilize carotid plaque by regulating the 5-lipoxygenase pathway in atherosclerotic rabbits and delay the progression of atherosclerosis by exerting anti-inflammatory effects. Expand
Impacts of COX-1 gene polymorphisms on vascular outcomes in patients with ischemic stroke and treated with aspirin.
In Chinese patients with ischemic stroke and treated with aspirin, CC genotype of rs1330344 may increase the risk of subsequent vascular events. Expand
Lesion patterns and mechanism of cerebral infarction caused by severe atherosclerotic intracranial internal carotid artery stenosis
Investigation of lesion patterns and mechanisms of infarcts produced by severe IICA stenosis found the hypoperfusion mechanism leading to BZI was more important for patients with severe Iica stenosis than for those with severe EICA stenotic. Expand
China Interventional Stroke Registry: Rationale and Study Design
The CISR is the first and the largest registry for angioplasty with/without stents in China and will provide the characteristics and outcomes of patients and the situation of adherence to guideline-based treatments under ‘real-world' conditions in China. Expand