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BACKGROUND Treatment of early-stage osteonecrosis of the femoral head (ONFH) with autologous implantation of iliac crest bone marrow-derived mononuclear cells, which contain tens of thousands of bone marrow mesenchymal stem cells (BMMSCs), recently achieved a promising outcome. METHODS One hundred patients with early-stage ONFH were recruited and randomly(More)
BACKGROUND Various head-preserving procedures have been used for young patients with osteonecrosis of the femoral head (ONFH) to avert the need for THA. However, none of these techniques are accepted universally because of the technical difficulties, complications, or mixed results that often are difficult to reproduce. QUESTIONS/PURPOSES We describe a(More)
The aim of this report is to present our experience on the use of the digital subtraction angiography (DSA) in selection of the vascularized greater trochanter bone grafting for the treatment of the osteonecrosis of femoral head (ONFH) in early stages. Between January 2005 and June 2007, DSA was used to evaluate the blood perfusion of the early stages ONFH(More)
OBJECTIVE To evaluate the clinical effect of treatment of osteonecrosis of the femoral head (ONFH) by minimally invasive vascularized bone grafting. METHODS 232 ONFH patients (232 hips), 146 males and 86 females, aged 39.8 (22 - 55), 114 being at the Ficat and Arlet stage II, 96 at stage III, and 22 at stage IV, were treated with minimally invasive(More)
Osteoclasts together with osteoblasts play pivotal roles in bone remodeling. The unique function and ability of osteoclasts to resorb bone makes them critical in both normal bone homeostasis and pathologic bone diseases such as osteoporosis and rheumatoid arthritis. Thus, new compounds that may inhibit osteoclastogenesis and osteoclast function may be of(More)
In this paper, an improved Prewitt algorithm for edge detection is proposed for the reason that the traditional Prewitt edge detection algorithm is sensitive to the noise. The traditional Prewitt edge detection operator only has two templates with horizontal and vertical directions. While the edge is in a plurality of directions, so operator with eight(More)
Osteonecrosis of the femoral head is a progressive disease. Without operative intervention, it most often results in collapse and deterioration of the joint. Many joint-preserving surgeries have been implemented, but no uniform treatment exists. The authors report a modified technique of tantalum rod implantation combined with vascularized iliac grafting(More)
BACKGROUND Osteonecrosis of the femoral head (ONFH) is the result of dysfunctional blood supply, but associations between specific damaged arteries, imaging changes and clinical sign require more understanding. We investigated characteristics of ONFH that pertain to blood supply, imaging appearance, and clinical feature to judge the prognosis of ONFH. (More)
OBJECTIVE To evaluate the effect of digital subtraction angiography (DSA) in evaluation of the hemodynamic changes after treatment of avascular osteonecrosis of femoral head with vascularized bone flaps. METHODS Fifty-four patients, 33 males and 21 females, 33 hips being at the stage II and 21 hips being at the stage III, were treated with vascularized(More)