Dewan Roshan Singh

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The posterolateral tunnel on the superior surface of the first cervical (atlas) vertebra is of normal occurrence in monkeys and other lower animals, but its presence in the form of a tunnel-like canal, for the passage of the third part of the vertebral artery over the posterior arch of the human atlas vertebra is not reported. The aim of the present study(More)
Alpha-foetoprotein (AFP) was found to be present in human foetal brain during early embryonic life. Antigenically and electrophoretically foetal brain AFP is similar to that found in human foetal serum. Like serum AFP it did not bind oestradiol. Developmental profile of the proteins in foetal brain was distinct from that observed in foetal serum, amniotic(More)
Tapentadol is a novel, centrally acting analgesic with dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechanism of action makes Tapentadol a useful analgesic to treat(More)
The caudal part of the fourth ventricle in adult rhesus monkeys, of both sexes, revealed the area postrema (AP) to be composed of bilateral spindle-shaped elevations located ventromedial to the gracile tubercles. Supraependymal (SE) elements, comprised of SE cells and/or fibre processes could be seen near the medial margin of a narrow oligociliated strip(More)
A 60-year-old woman posted for percutaneous nephrolithotomy with ureterolithotripsy was found to have a history of hypertension and ischemic heart disease from past 6 months on regular treatment. Pulse rate was irregularly irregular in a range of 56-60/min, unresponsive to atropine, with a sinus pause on the electrocardiogram. Although the patient was(More)
Many anti-emetics are used in clinical practice. Palonosetron hydrochloride is one of them. It is a novel, centrally acting antiemetic, and anti-nausea agent. This drug is an antagonist of serotonin receptor subtype 3 (5-HT3). This drug has longer duration of action which makes it useful in the prevention and treatment of acute and delayed onset of nausea(More)
Sugammadex (ORG 25969) is a unique neuromuscular reversal drug; a novel cyclodextrin, the first in a new class of selective relaxant binding agents, which reverse neuromuscular blockade (NMB) with the aminosteroid non-depolarizing muscle relaxants rocuronium and vecuronium. Sugammadex can reverse moderate or deep NMB. The clinical use of sugammadex promises(More)
The ependymal structure of the fourth ventricle floor of adult rhesus monkeys was investigated using both scanning and transmission electron microscopy. Each half of the floor exhibited dense ciliation which decreased towards the median sulcus. The area postrema and the facial colliculus lacked cilia and were covered with non-ciliated ependymal cells. Along(More)