Devin L McCaslin

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The purpose of this study was to test the effects of intense tone exposure on the spontaneous activity of multiunit clusters in the mammalian dorsal cochlear nucleus (DCN). Adult hamsters (60-101 days of age) were exposed to a 10 kHz tone at levels between 125 and 130 dB SPL for a period of 4 hours. The effects of tone exposure were studied following a(More)
Previous studies have shown that the dorsal cochlear nucleus exhibits increased spontaneous activity after exposure to intense sound. Such increases were apparent 1-2 months after the exposure and were generally proportional to the shift in response thresholds induced by the same exposure. The purpose of the present study was to determine whether this(More)
BACKGROUND Stimulus-evoked electromyographic changes can be recorded from the extraocular muscles. These short-latency negative-polarity evoked myogenic potentials are called ocular vestibular evoked myogenic potentials (oVEMPs). To date there has not yet been a large-scale study examining the effects of age on the amplitude, latency, threshold, and(More)
There have been disparate findings reported previously by investigators who have examined differences in the cortically generated N1 (i.e., N100) from control and tinnitus samples. Investigators have employed differing stimulation paradigms applied to relatively small subject samples. Accordingly, it is not surprising that there has been no unanimity in the(More)
The purpose of this investigation was to study the ameliorating effects of four agents on cisplatin-induced ototoxicity. Hamsters were given a series of five cisplatin injections either alone or in combination with sodium thiosulfate (STS), diethyldihydrothiocarbamate (DDTC), and S-2(3-aminopropylamino) ethylphosphorothioic acid (WR-2721), or fosfomycin.(More)
OBJECTIVES The purpose of this investigation was to determine whether a predictable relationship existed between self-reported dizziness handicap and video Head Impulse Test (vHIT) results in a large sample of patients reporting to a dizziness clinic. Secondary objectives included describing the characteristics of the vHIT ipsilesional and contralesional(More)
The purposes of these investigations were to (1) evaluate tinnitus loudness measures of unskilled normal listeners asked to imagine that they are experiencing a constant monaural tonal tinnitus and (2) compare the performance of these listeners to that of a sample of patients with tinnitus. Subgroups of 24 patients participated in two investigations.(More)
Factors such as anxiety, depression, somatic awareness, autonomic symptoms, and differences in coping strategies are known to affect dizziness handicap. We studied these factors in 63 consecutive "dizzy" patients. This sample was subgrouped into normals and patients with benign paroxysmal positional vertigo, compensated and uncompensated unilateral(More)
The purpose of this investigation was to determine whether there exists in the scientific literature support for a cause and effect relationship between tinnitus and suicide. MEDLINE and HealthStar databases were queried using the combined search terms "tinnitus" and "suicide" over the time period from 1966 to 2001 for MEDLINE and from 1975 to 2001 for(More)
The gamma band response (GBR) is an exogenous, cortically generated, event-related potential that occurs between 20- and 170-msec post-stimulus onset. The auditory GBR is superimposed on the transient evoked middle and long latency cortical auditory evoked potentials and demonstrates a peak spectral frequency between 30 and 40 Hz. The present investigations(More)