BACKGROUND Our aim was to assess the value of brain apparent diffusion coefficient (ADC) in Intra Cytoplasmic Sperm Injection (ICSI) and spontaneously conceived preterm singletons. METHODS Twenty ICSI-conceived preterm singletons and 20 gestational age matched spontaneously conceived preterm singletons were studied. All subjects underwent… (More)
Pelizaeus-Merzbacher disease (PMD) is a rare dysmyelinating disorder of the CNS. The cause is abnormal production of proteolipid protein–1 (PLP-1)that is a principal components of myelin. It is characterised by rotatory nistagmus, early muscular hypotonia, head shake, ataxia, spasticity and mental retardation. The diagnosis of PMD is with clinical findings,… (More)
We report on a male infant with Cornelia de Lange syndrome and bilateral split feet. Bilateral split feet do not appear to have ever been a reported feature in any of the published cases of Cornelia de Lange syndrome.