Derrick Mok Kwee Heng

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Patients with metastatic nasopharyngeal carcinoma have variable survival outcomes. We previously designed a scoring system to better prognosticate these patients. Here, we report results on validation of this new prognostic index score in a separate cohort of patients. Clinical features and laboratory parameters were examined in 172 patients with univariate(More)
The survival outcome of patients with systemic cancer differs significantly between individuals even within the same tumour type. We set out to illustrate this by analysing the factors determining survival in patients with metastatic disease from nasopharyngeal carcinoma (NPC) and to design a scoring system based on these prognostic factors. Patients(More)
BACKGROUND The objective of the current study was to describe the survival of nasopharyngeal carcinoma (NPC) patients in Singapore, verify the prognostic value of the revised 1997 TNM staging system, and develop a multivariate prognostic model for NPC. In addition, the authors also examined the prognostic value of characteristics of lymph node spread and(More)
OBJECTIVES To compare hospital length of stay (LOS) and outcome after stroke between patients in a stroke unit offering combined acute and rehabilitation services and patients treated elsewhere in New South Wales. DESIGN Retrospective audit of two hospital databases (Diagnosis-Related Groups [DRG] database and Australian National Subacute Non-Acute(More)
The Ministry of Health publishes national clinical practice guidelines to provide doctors and patients in Singapore with evidence-based guidance on managing important medical conditions. This article reproduces the introduction and executive summary (with key recommendations from the guidelines) from the Ministry of Health clinical practice guidelines on(More)
OBJECTIVE To describe an outbreak of severe acute respiratory syndrome (SARS) in a tertiary hospital in Singapore, linked to an index patient with atypical presentation, and the lessons learnt from it. DESIGN Descriptive study. SETTING A tertiary hospital in Singapore. PARTICIPANTS Patients, healthcare workers, and visitors who contracted SARS in(More)
We studied the relationship between different ethnic groups, obstructive sleep apnoea (OSA) and ischaemic heart disease. Four hundred and thirty-two inpatients from the medical wards were interviewed. Limited overnight sleep studies were done in 129 of those who had habitual snoring, daytime sleepiness based on an Epworth sleepiness scale of 8 or more, or a(More)
1 Department of Medicine, National University Health System, Singapore 2 Epidemiology & Disease Control Division, Ministry of Health, Singapore 3 Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore Address for Correspondence: Dr Hsu Li Yang, Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074.(More)
5575 Background: Patients with metastatic undifferentiated nasopharyngeal carcinoma (mets NPC) comprise a heterogeneous group with varying survival duration. Previously, we retrospectively analyzed the factors determining survival in these patients and designed a prognostic index score (PIS). (Ong YK et al; proc ASCO 2001) We now present our analysis on a(More)
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