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This survey of the clinical and epidemiological features of human cowpox, a rare but relatively severe zoonotic infection, is based on 54 cases, many unpublished, which we have studied since 1969. Patients present with painful, haemorrhagic pustules or black eschars, usually on the hand or face, accompanied by oedema, erythema, lymphadenopathy, and systemic(More)
  • Derrick Baxby, B. J. Hill
  • 1971
The diagnostic characteristics of four poxviruses isolated from infected Indian buffaloes have been determined. Three isolates were all very similar, differing in only minor properties. They were serologically indistinguishable from vaccinia virus and had the same ceiling temperature as it, and we regard them as slightly different strains of vaccinia virus.(More)
This paper describes virological and epidemiological features of an infection which killed two of three affected cheetahs at Whipsnade Park in 1977. Two animals had profuse skin lesions and the third had an acute haemorrhagic pneumonia. The outbreak was shown to be caused by cowpox virus. Cowpox virus is believed to circulate in small wild animals, but the(More)
Twelve separate outbreaks of confirmed cowpox, 10 involving humans, were reviewed. Six of the patients, including three children, had severe infections and five were admitted to hospital. In three outbreaks both people and cows were affected but it was not known how the infections entered the herds. In seven outbreaks no direct contact with cattle was(More)
Features are described of a new staining method for the detection of Cryptosporidium oocysts in faeces. Smears, fixed in acid-methanol, are stained with heated safranin and counterstained with methylene blue. Oocysts stain a vivid orange-pink and are easily recognized. The method is rapid and simple with little source of error. The method is more sensitive(More)
OBJECTIVE The objective was to compare evidence of the effectiveness, costs and safety of the traditional parenteral antibiotic-only approach against that gathered from 53 randomised trials involving more than 8,500 patients and six meta-analyses on selective decontamination of the digestive tract (SDD) to control infection on the intensive care unit (ICU).(More)
Human cowpox is a rare but relatively severe infection of interest because of its links with Edward Jenner and the introduction of smallpox vaccine and, more recently, because of re-evaluation of the epidemiology of the infection. This indicates that cowpox is not enzootic in cattle, relegates the cow to a minor role, and emphasizes the importance of feline(More)