Deren Wang

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OBJECTIVE The association between metabolic syndrome (MS) and the risk of cognitive impairment or dementia remains unclear. In this article, we systematically review studies on the risk of cognitive disorders in patients with MS to determine the strength of the association between MS and cognitive decline. METHODS Electronic databases through December(More)
BACKGROUND It had been assumed that suppressing the undamaged contralesional motor cortex by repetitive low-frequency transcranial magnetic stimulation (rTMS) or increasing the excitability of the damaged hemisphere cortex by high-frequency rTMS will promote function recovery after stroke. OBJECTIVES To assess the efficacy and safety of rTMS for improving(More)
BACKGROUND We aimed to systematically overview published systematic reviews and meta-analyses in order to identify whether and when acupuncture is an effective treatment for stroke and stroke-related disorders. We also hoped to identify the best directions for future research in this area. METHODS Systematic reviews and meta-analyses of randomized(More)
Reduced blood hemoglobin levels may impair oxygen delivery to the brain and hinder neurological improvement. We prospectively registered consecutively hospitalized Chinese patients with acute ischemic stroke within 24 hours of symptom onset to investigate whether anemia on admission influences case fatality and functional outcome of acute ischemic stroke at(More)
Few prospective studies have examined the frequency, predictors and long-term outcomes of spontaneous hemorrhagic transformation (HT) in patients with ischemic stroke not receiving thrombolytic treatment. We prospectively enrolled a consecutive cohort of 407 patients with ischemic stroke who were admitted within one month of stroke onset. In patients who(More)
BACKGROUND Little information is available on Asian patients over 80 years with stroke. We aimed to investigate characteristics of the very elderly ischemic stroke hospitalized patients in China. METHODS We prospectively enrolled consecutive patients with acute ischemic stroke from March, 2002 to October, 2008 into the analysis. Patients were divided into(More)
The association between chronic kidney disease and spontaneous hemorrhagic transformation (HT) in patients with acute ischemic stroke is seldom reported. We performed this study to identify whether reduced estimated glomerular filtration rate (eGFR) is associated with spontaneous HT in acute ischemic stroke patients, and examine whether the association(More)
Ischemic stroke is a severe complication of rheumatic heart disease (RHD), but data about its incidence and case-fatality in RHD patients' population is unclear. We aimed to perform a systematic review of the literature to better define the incidence, prevalence and case-fatality of stroke in patients with RHD, and to estimate the proportion of RHD in(More)
BACKGROUND AND PURPOSE Diabetes is common in acute stroke and is associated with worse outcome in ischemic stroke, but its influence on intracerebral hemorrhage (ICH) remains controversial. We examined the association between diabetes and clinical outcome in a large hospitalized population of Chinese patients with ICH. METHODS We prospectively enrolled(More)