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  • Ana Moretón Fernández, Derek Leroith
  • Medicine
  • Advances in experimental medicine and biology
  • 2005
  • The skeletal muscle is composed of striated muscle tissue under voluntary control and plays a key role in many activities such as the maintenance of posture, the locomotion, the speech and theContinue Reading
  • Klara Sjögren, Jiajian Liu, +8 authors Claes Ohlsson
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1999 (First Publication: 8 June 1999)
  • The body growth of animals is regulated by growth hormone and IGF-I. The classical theory of this regulation is that most IGF-I in the blood originates in the liver and that body growth is controlledContinue Reading
  • Ann Hellstrom, Carole A. Perruzzi, +10 authors Lois E. H. Smith
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2001 (First Publication: 1 May 2001)
  • Retinopathy of prematurity is a blinding disease, initiated by lack of retinal vascular growth after premature birth. We show that lack of insulin-like growth factor I (IGF-I) in knockout miceContinue Reading
  • Marcelina Párrizas, Alan R. Saltiel, Derek Leroith
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 1997 (First Publication: 3 January 1997)
  • The role of insulin-like growth factor 1 (IGF-1) in preventing apoptosis was examined in differentiated PC12 cells. Induction of differentiation was achieved using nerve growth factor, and apoptosisContinue Reading