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- Carl-Philipp Heisenberg, Masazumi Tada, +6 authors Stephen W. Wilson
- Nature
- 2000
Vertebrate gastrulation involves the specification and coordinated movement of large populations of cells that give rise to the ectodermal, mesodermal and endodermal germ layers. Although many of the… (More)
- Alexander F Schier, Stephan C. F. Neuhauss, +9 authors W Driever
- Development
- 1996
In a large scale mutagenesis screen for embryonic mutants in zebrafish, we have identified 63 mutations in 24 loci affecting the morphogenesis of the zebrafish brain. The expression of marker genes… (More)
- Kerstin Howe, Matthew D Clark, +174 authors Derek L. Stemple
- Nature
- 2013
Zebrafish have become a popular organism for the study of vertebrate gene function. The virtually transparent embryos of this species, and the ability to accelerate genetic studies by gene knockdown… (More)
- Erika A. Bosman, Andrew C. Penn, J Christian Ambrose, Ross N.W. Kettleborough, Derek L. Stemple, Karen P. Steel
- Human molecular genetics
- 2005
Mouse ENU mutagenesis programmes have yielded a series of independent mutations on proximal chromosome 4 leading to dominant head-bobbing and circling behaviour due to truncations of the lateral… (More)
- Wolfgang Driever, Lila Solnica-Krezel, +9 authors Carol L. Boggs
- Development
- 1996
Systematic genome-wide mutagenesis screens for embryonic phenotypes have been instrumental in the understanding of invertebrate and plant development. Here, we report the results from the first… (More)
- Michael James Parsons, Steven M Pollard, +4 authors Derek L. Stemple
- Development
- 2002
Basement membranes are thought to be essential for organ formation, providing the scaffold on which individual cells organize to form complex tissues. Laminins are integral components of basement… (More)
- Lilianna Solnica-Krezel, Derek L. Stemple, +8 authors W Driever
- Development
- 1996
One of the major challenges of developmental biology is understanding the inductive and morphogenetic processes that shape the vertebrate embryo. In a large-scale genetic screen for zygotic effect,… (More)
- Pedro Antonio Pérez-Mancera, Alistair G. Rust, +33 authors David A Tuveson
- Nature
- 2012
Pancreatic ductal adenocarcinoma (PDA) remains a lethal malignancy despite much progress concerning its molecular characterization. PDA tumours harbour four signature somatic mutations in addition to… (More)
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo.
- Didier Y. R. Stainier, Brunhilde Fouquet, +12 authors Mark C Fishman
- Development
- 1996
As part of a large-scale mutagenesis screen of the zebrafish genome, we have identified 58 mutations that affect the formation and function of the cardiovascular system. The cardiovascular system is… (More)
- Stephan C. F. Neuhauss, Lila Solnica-Krezel, +6 authors Wolfgang Driever
- Development
- 1996
In a large-scale screen for mutations affecting embryogenesis in zebrafish, we identified 48 mutations in 34 genetic loci specifically affecting craniofacial development. Mutants were analyzed for… (More)