Derek G. Tilley

  • Citations Per Year
Learn More
Accurate predictions of pressure surges are crucial in many fluid-line systems. There are several techniques available for modelling flow transients in hydraulic pipelines, offering different advantages and disadvantages and therefore suiting different applications. In this paper four modelling methods are evaluated in terms of accuracy, computational(More)
This paper explores the potential of isotope V/Q lung scans to quantify lung disease. Areas of restricted perfusion in subjects with a pulmonary embolus (PE) were identified in 3D reconstructions of V/Q images achieved using anatomical data from the Visible Human Project. From these, the extent of lung damage was quantified. Significant differences in the(More)
A multi-technique approach to modelling artificially ventilated patients on the adult general intensive care unit (ICU) is proposed. Compartmental modelling techniques were used to describe the mechanical ventilator and the flexible hoses that connect it to the patient. 3D CFD techniques were used to model flow in the major airways and a Windkessel style(More)
This article describes the development of a comprehensive mathematical model of the human cardiopulmonary system that combines the respiratory and cardiovascular systems and their associated autonomous nervous control actions. The model is structured to allow the complex interactions between the two systems and the responses of the combined system to be(More)
This paper describes two approaches to modelling lung disease: one based on a multicompartment statistical model with a log normal distribution of ventilation perfusion ratio ( _ V= _ Q) values; and the other on a bifurcating tree which emulates the anatomical structure of the lung. In the statistical model, the distribution becomes bimodal, when the _ V= _(More)
  • 1