Derek A Seehausen

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The lethal genetic disease cystic fibrosis is caused predominantly by in-frame deletion of phenylalanine 508 in the cystic fibrosis transmembrane conductance regulator (CFTR). F508 is located in the first nucleotide-binding domain (NBD1) of CFTR, which functions as an ATP-gated chloride channel on the cell surface. The F508del mutation blocks CFTR export to(More)
BACKGROUND Spica casting is the standard of care for femur fractures in children up to 6 years of age. The indications for surgery are controversial. We sought to compare immediate spica casting (Spica) and flexible intramedullary nailing [titanium elastic nailing (TEN)] in a group of children ages 2 to 6 years. We hypothesized that young children can be(More)
STUDY DESIGN This was a retrospective review of posterior spinal fusion surgical procedures in patients diagnosed with adolescent idiopathic scoliosis (AIS) or neuromuscular scoliosis (NMS). OBJECTIVE The purpose was to determine if the first assistant's training experience is associated with outcomes in AIS and NMS surgical procedures. SUMMARY OF(More)
BACKGROUND The purpose of this study was to determine the early factors associated with the need for surgical interventions in patients with idiopathic clubfoot treated with the Ponseti method. METHODS All patients with idiopathic clubfoot treated with Ponseti method at our institution with >3 years of follow-up were evaluated. Age at presentation,(More)
OBJECTIVE To determine the frequency and clinical significance of postoperative fever in pediatric patients undergoing posterior spinal fusion (PSF). STUDY DESIGN A retrospective chart review was performed for consecutive patients undergoing PSF at a single institution between June 2005 and April 2011, with a minimum of 2-year follow up. Exclusion(More)
STUDY DESIGN Multicenter, retrospective cohort study. OBJECTIVES The purpose of this study is to determine how the amount of residual lowest instrumented vertebra (LIV) tilt correlates with radiographic measurements. SUMMARY OF BACKGROUND DATA When performing a selective thoracic posterior spinal fusion for adolescent idiopathic scoliosis (AIS), the LIV(More)
BACKGROUND Varying casting techniques are used after surgical treatment of pediatric supracondylar humerus fractures. The goals are to maintain fracture reduction, while accommodating soft tissue swelling and minimizing the risk of compartment syndrome. METHODS A retrospective chart review of consecutive patients aged 0 to 14 years who underwent surgical(More)
BACKGROUND Accessory navicular (AN) is a common anatomic variant that is known to cause medial foot pain. Surgery may be required for excision if conservative measures fail. Often, the medial border of the navicular is excised in addition to the AN during surgery. The purpose of this radiographic study is to determine if the presence of an AN is associated(More)
STUDY DESIGN Retrospective review of 1 surgeon's posterior spinal fusion cases. OBJECTIVES To assess the safety and efficacy of using power tools versus using manual tools to create pedicle tracts and place pedicle screws. SUMMARY OF BACKGROUND DATA This is the first study to report on the safety and efficacy of pedicle tract creation and pedicle screw(More)
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