Dereck Salisbury

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BACKGROUND Reactive oxygen and nitrogen species, known as free radicals, play a key role in the etiology and progression of atherosclerotic cardiovascular disease by creating vascular oxidative stress. PURPOSE This review will discuss current biological research about the enzymatic and nonenzymatic sources of oxidative stress, free radical chemistry, and(More)
BACKGROUND Immune system activation and inflammation are intricately involved in the development and progression of atherosclerosis. PURPOSE The purposes of this review are to (a) discuss effects of inflammation and the immune system across the lifespan of atherosclerotic plaque, (b) review current recommended testing techniques for assessing inflammation(More)
BACKGROUND Older adults with Alzheimer's disease (AD) may be unable to perform treadmill testing due to balance issues. We investigated whether older adults with AD could successfully complete a peak cycle ergometer test. METHODS Peak oxygen consumption (peak [Formula: see text]) assessed via a cycle ergometer test in 44 participants with AD (age 78.4 ±(More)
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