Dennis W. X. Zhu

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BACKGROUND Current guidelines recommend stopping oral anticoagulation and starting bridging anticoagulation with intravenous heparin or subcutaneous enoxaparin when implanting a pacemaker or defibrillator in patients at moderate or high risk for thromboembolic events. A limited body of literature suggests that device surgery without cessation of oral(More)
Ten years after orthotopic cardiac transplantation, a 56-year-old man developed recurrent presyncope and syncope. A 24-hour ambulatory electrocardiographic recording did not document significant arrhythmic events. A head-up tilt table test was negative. An electrophysiologic study revealed dual atrioventricular (AV) nodal physiology and inducible typical(More)
The purpose of this study was to evaluate predictors of appropriate therapy in patients with implantable cardioverter-defibrillators (ICD) for primary prevention of sudden cardiac death. A retrospective cohort of 321 patients with systolic heart failure undergoing ICD placement for primary prevention of sudden cardiac death was queried with a mean follow-up(More)
The AngioJet Rheolytic Thrombectomy System (Possis Medical, Inc., Minneapolis, Minnesota) is an effective thrombectomy device, but it may cause bradycardias ranging from mild bradycardia to asystole and hypotension in some patients. The incidence appears to be higher with the proximity of the device to the heart. Several hypotheses have attempted to explain(More)
The aim of this investigation was to determine additional predisposing factors of pocket hematoma formation in patients undergoing anti-arrhythmic device surgery. Initially, we performed a retrospective chart review of 459 patients on warfarin therapy who underwent anti-arrhythmic device surgery (pacemaker or defibrillator implantation, generator(More)
BACKGROUND Patients with severely depressed left ventricular ejection fractions (LVEFs) receive implantable cardioverter-defibrillators (ICDs) for the primary prevention of sudden death. In some patients, however, LVEF may improve or even normalize over time. Limited data are available on the incidence of appropriate antitachycardia therapy, including(More)
We present two cases of cardiac arrest, presumably attributable to apical hypertrophic cardiomyopathy(HCM). The first case was a 37-year-old Asian man known to have an apical HCM and was successfully resuscitated from an "out of hospital" ventricular fibrillation arrest. He underwent an electrophysiological study that was unable to induce tachyarrhythmias,(More)
BACKGROUND In patients with a functional Sprint Fidelis lead at generator replacement, the manufacturer recommended to either continue to use the existing lead or replace it with a new lead. For those patients who continue to use a functional Fidelis lead, the risk of inappropriate shocks remains present if the lead fails in the future. OBJECTIVE We(More)
Objective: A systematic review of the literature was conducted relating to the continuation of warfarin therapy at the time of coronary angiography, with or without percutaneous coronary intervention, to determine the bleeding risk of these patients. Methods: A search of a major electronic database was independently conducted by two reviewers from 1960 to(More)