Dennis Jones

Publications12
h-index7
Citations281
Highly Influential Citations9
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  • Publications
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Endothelial-Specific Transgenesis of TNFR2 Promotes Adaptive Arteriogenesis and Angiogenesis
  • Y. Luo, Z. Xu, +4 authors W. Min
  • Biology, Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 1 July 2010
Objective—We have previously shown that the tumor necrosis factor receptor 2 (TNFR2) protein is highly upregulated in vascular endothelium in response to ischemia, and a global deletion of TNFR2 in… Expand
  • 30
  • 3
ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets.
Lymphatic vessels (LVs) are important structures for antigen presentation, for lipid metabolism, and as conduits for tumor metastases, but they have been difficult to visualize in vivo. Prox1 is a… Expand
  • 60
  • 2
Growth and Immune Evasion of Lymph Node Metastasis
Cancer patients with lymph node (LN) metastases have a worse prognosis than those without nodal disease. However, why LN metastases correlate with reduced patient survival is poorly understood.… Expand
  • 42
  • 2
Endothelial-Specific Expression of Mitochondrial Thioredoxin Promotes Ischemia-Mediated Arteriogenesis and Angiogenesis
  • Shengchuan Dai, Yun He, +6 authors W. Min
  • Biology, Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 1 April 2009
Objective—Thioredoxin-2 (Trx2), a major antioxidant protein in mitochondria, enhances nitric oxide bioavailability and inhibits ASK1-dependent apoptosis in endothelial cells (ECs). However, the in… Expand
  • 60
  • 1
  • PDF
Mirtron MicroRNA-1236 Inhibits VEGFR-3 Signaling During Inflammatory Lymphangiogenesis
Objective—Vascular endothelial growth factor receptor(VEGFR)-3 is a critical regulator of developmental and adult vasculogenesis and lymphangiogenesis through its interactions with select members of… Expand
  • 40
  • 1
  • PDF
Functional Analyses of the Bone Marrow Kinase in the X Chromosome in Vascular Endothelial Growth Factor–Induced Lymphangiogenesis
  • Dennis Jones, Z. Xu, +4 authors W. Min
  • Biology, Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 23 September 2010
Objective—The goal of this study was to investigate the novel hypothesis that bone marrow kinase in the X chromosome (Bmx), an established inflammatory mediator of pathological angiogenesis, promotes… Expand
  • 21
Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.
Bmx, [corrected] also known as Etk, is a member of the Tec family of nonreceptor tyrosine kinases. Bmx is expressed mainly in arterial endothelia and in myeloid hematopoietic cells. Bmx regulates… Expand
  • 28
  • PDF
Abstract 3022: Lymph node metastasis in solid tumors: A marker or driver of disease progression
Background: The presence of lymph node metastasis in patients with solid tumors is associated with tumor aggressiveness, poorer prognosis and the recommendation for systemic therapy. However, whether… Expand
Defining the Role and Responsibility of the Fire Service within Homeland Security
Abstract : Many fire service providers (FSPs) do not adequately address homeland security. While some FSPs in the United States have dedicated homeland security divisions or operational practices,… Expand
Abstract PR06: Formation of lymph node metastases is not angiogenesis dependent
Background: To date, antiangiogenic therapy has failed to improve overall survival in cancer patients when used in the adjuvant setting. The presence of lymph node metastases dictate treatment… Expand
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