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Arteriosclerosis, thrombosis, and vascular…
OBJECTIVE
Thioredoxin-2 (Trx2), a major antioxidant protein in mitochondria, enhances nitric oxide bioavailability and inhibits ASK1-dependent apoptosis in endothelial cells (ECs). However, the in… Continue Reading
Lymphatic vessels (LVs) are important structures for antigen presentation, for lipid metabolism, and as conduits for tumor metastases, but they have been difficult to visualize in vivo. Prox1 is a… Continue Reading
OBJECTIVE
We have previously shown that the tumor necrosis factor receptor 2 (TNFR2) protein is highly upregulated in vascular endothelium in response to ischemia, and a global deletion of TNFR2 in… Continue Reading
Cancer patients with lymph node (LN) metastases have a worse prognosis than those without nodal disease. However, why LN metastases correlate with reduced patient survival is poorly understood.… Continue Reading
Bmx, [corrected] also known as Etk, is a member of the Tec family of nonreceptor tyrosine kinases. Bmx is expressed mainly in arterial endothelia and in myeloid hematopoietic cells. Bmx regulates… Continue Reading
Arteriosclerosis, thrombosis, and vascular…
OBJECTIVE
Vascular endothelial growth factor receptor(VEGFR)-3 is a critical regulator of developmental and adult vasculogenesis and lymphangiogenesis through its interactions with select members of… Continue Reading
Arteriosclerosis, thrombosis, and vascular…
OBJECTIVE
The goal of this study was to investigate the novel hypothesis that bone marrow kinase in the X chromosome (Bmx), an established inflammatory mediator of pathological angiogenesis, promotes… Continue Reading
Background: The presence of lymph node metastasis in patients with solid tumors is associated with tumor aggressiveness, poorer prognosis and the recommendation for systemic therapy. However, whether… Continue Reading
Abstract : Many fire service providers (FSPs) do not adequately address homeland security. While some FSPs in the United States have dedicated homeland security divisions or operational practices,… Continue Reading
Background: To date, antiangiogenic therapy has failed to improve overall survival in cancer patients when used in the adjuvant setting. The presence of lymph node metastases dictate treatment… Continue Reading