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I nformation security problems cost millions of dollars for US companies and billions for the overall US economy, according to a joint survey by the Computer Security Institute and the US Federal Bureau of Investigation Nowadays, the question is not whether organizations need more security, but how much to spend for added security.And yet investing in IT(More)
The purpose of this report was to characterize the dynamics of the gene expression cascades induced by an IFN-␤-1a treatment regimen in multiple sclerosis patients and to examine the molecular mechanisms potentially capable of causing heterogeneity in response to therapy. In this open-label pharmacodynamic study design, peripheral blood was obtained from(More)
Large dynamic nuclear polarization signal enhancements (up to a factor of 100) were obtained in the solid-state magic-angle spinning nuclear magnetic resonance (NMR) spectra of arginine and the protein T4 lysozyme in frozen glycerol-water solutions with the use of dynamic nuclear polarization. Polarization was transferred from the unpaired electrons of(More)
Giant magnetoresistive biosensors possess great potential in biomedical applications for quantitatively detecting magnetically tagged biomolecules. Magnetic sensing does not suffer from the high background levels found in optical sensing modalities such as the enzyme linked immunosorbent assay translating into a technology with higher sensitivity. However,(More)
PURPOSE To investigate the effects of interferon-beta-1a (IFN-beta-1a) on the trafficking of cell populations in peripheral blood cells of multiple sclerosis (MS) patients. METHODS In this open-label pharmacodynamic study, peripheral blood was obtained from 10 relapsing-remitting (RR) MS patients just prior to and at 1, 2, 4, 8, 24, 48, 120, and 168 h(More)
ii ABSTRACT The California Forest Practice Rules (FPRs) (Title 14, California Code of Regulations) are designed in large part to protect water quality and aquatic habitat in forested watersheds during and after silviculture activities (Figure 1). The critical questions then become: 1) At what rate are the water quality related FPRs being properly(More)
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