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  • Silvia Schanz, Dennis Castor, Franziska Fischer, Josef Jiricny
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2009 (First Published: 7 April 2009)
  • In eukaryotic mismatch repair (MMR), degradation of the error-containing strand initiates at nicks or gaps that can be up to a kilobase away from the mispair. These discontinuities may be the ends ofContinue Reading
  • Christian Vettermann, Dennis Castor, Andrea Mekker, Bertran Gerrits, Michael Karas, Hans-Martin Jäck
  • Biology, Medicine
  • Proteomics
  • 2011 (First Published: 1 April 2011)
  • The final step of B-cell maturation is to differentiate into plasma cells, a process that is accompanied by gross changes in subcellular organization to enable antibody secretion. To betterContinue Reading
  • Roger M Wanner, Dennis Castor, Carolin Güthlein, Erik C Böttger, Burkhard Springer, Josef Jiricny
  • Biology, Medicine
  • Journal of bacteriology
  • 2009 (First Published: 15 October 2009)
  • Spontaneous hydrolytic deamination of DNA bases represents a considerable mutagenic threat to all organisms, particularly those living in extreme habitats. Cytosine is readily deaminated to uracil,Continue Reading