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  • Dennis B. Lubahn, Jeffrey S. Moyer, Tony Golding, John F. Couse, Kenneth S. Korach, Oliver Smithies
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 1993 (First Publication: 1 December 1993)
  • Estrogen receptor and its ligand, estradiol, have long been thought to be essential for survival, fertility, and female sexual differentiation and development. Consistent with this proposed crucialExpand
  • John F. Couse, Sylvia Curtis, +5 authors Kenneth S. Korach
  • Biology, Medicine
  • Molecular endocrinology
  • 1995 (First Publication: 1 November 1995)
  • We employed homologous recombination in mouse embryonic stem cells to disrupt the estrogen receptor (ER) gene. Subsequently generated mice that are homozygous for the gene disruption, termed ERKO,Expand
  • Dennis B. Lubahn, David R. Joseph, Patrick M Sullivan, Huntington F. Willard, Frank S. French, Elizabeth A. M. Wilson
  • Medicine, Biology
  • Science
  • 1988 (First Publication: 15 April 1988)
  • The androgen receptor (AR) mediates the actions of male sex steroids. Human AR genomic DNA was cloned from a flow-sorted human X chromosome library by using a consensus nucleotide sequence from theExpand