Dennis A. Noe

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4-Ipomeanol (IPO), a naturally occurring pulmonary toxin, is the first cytotoxic agent to undergo clinical development based on a biochemical-biological rationale as an antineoplastic agent targeted specifically against lung cancer. This rationale is based on preclinical observations that met abolic activation and intracellular binding of IPO, as well as(More)
Trained weight lifters lift heavy loads without a concomitant degree of acute low-back injuries. To study the process by which large loads are lifted with minimal injury, integrated electromyographic signals were recorded from four large muscle groups: gluteus maximus, quadriceps, latissimus dorsi, and erector spinae in 4 weight lifters and 11 asymptomatic(More)
Electromyographic signals (EMG) from surface electrodes over the vastus medialis, rectus femoris and vastus lateralis were monitored during isometric knee extension for 10 TKA patients and 6 control subjects. No significant side-to-side differences in normalized EMG signals from any of the monitored muscles were found when the left and right legs of the(More)
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