Denja Baumgartner

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The core region of LPS has a relatively similar structure in various Gram-negative bacteria, whereas the outermost O side chains are responsible for the marked anti-genic diversity among Gram-negative bacteria. O side chain-specific antibodies protect against homologous strains but not against heterologous strains in animal models. The core region of LPS is(More)
Streptococcus pneumoniae causes several human diseases, including pneumonia and meningitis, in which pathology is associated with an excessive inflammatory response. A major inducer of this response is the cholesterol dependent pneumococcal toxin, pneumolysin. Here, we measured the amount of inflammatory cytokine CXCL8 (interleukin (IL)-8) by ELISA released(More)
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